Evidence map›Paper›PMID 37108282›Full record

ArticleInternational journal of molecular sciences2023

Tetrahydrocannabivarin (THCV) Protects Adipose-Derived Mesenchymal Stem Cells (ASC) against Endoplasmic Reticulum Stress Development and Reduces Inflammation during Adipogenesis.

Anna Kowalczuk, Krzysztof Marycz, Justyna Kornicka, Sylwia Groborz, Justyna Meissner, Malwina Mularczyk

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Anna KowalczukNational Medicines Institute, Chełmska 30/34, 00-725 Warsaw, Poland.
Krzysztof MaryczInternational Institute of Translational Medicine, Jesionowa 11, 55-114 Malin, Poland.
Justyna KornickaFaculty of Electronics, Photonics and Microsystems, Wrocław University of Science and Technology, Smoluchowskiego 25, 50-372 Wrocław, Poland.ORCID 0000-0003-4765-4776
Sylwia GroborzInternational Institute of Translational Medicine, Jesionowa 11, 55-114 Malin, Poland.
Justyna MeissnerDepartment of Experimental Biology, Faculty of Biology and Animal Science, Wrocław University of Environmental and Life Sciences, Norwida 27B, 50-375 Wrocław, Poland.ORCID 0000-0002-8667-908X
Malwina MularczykInternational Institute of Translational Medicine, Jesionowa 11, 55-114 Malin, Poland.ORCID 0000-0001-8189-9545
Wrocław University of Environmental and Life Sciences · PLNarodowy Instytut Leków · PLWrocław University of Science and Technology · PL

Funding

Wroclaw University of Environmental and Life Sciences POWR.03.05.00-00-Z062/18
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) fulfills essential duties in cell physiology, and impairment of this organelle's functions is associated with a wide number of metabolic diseases. When ER stress is generated in the adipose tissue, it is observed that the metabolism and energy homeostasis of the adipocytes are altered, leading to obesity-associated metabolic disorders such as type 2 diabetes (T2D). In the present work, we aimed to evaluate the protective effects of Δ9-tetrahydrocannabivarin (THCV, a cannabinoid compound isolated from

Indexed as

CannabinoidsDiabetes Mellitus, Type 2Mesenchymal Stem CellsAdipogenesisEndoplasmic Reticulum StressHumansInflammationCannabinoidsadipocyteendoplasmic reticulum (ER)Δ9-tetrahydrocannabivarin

Identifiers

PMID37108282
PMCPMC10138341
OpenAlexW4365146755

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.