Evidence map›Paper›PMID 37108270›Full record

ArticleInternational journal of molecular sciences2023

Membrane Lesions and Reduced Life Span of Red Blood Cells in Preeclampsia as Evidenced by Atomic Force Microscopy.

Ina Giosheva, Velichka Strijkova, Regina Komsa-Penkova, Sashka Krumova, Ariana Langari, Avgustina Danailova, Stefka G Taneva, Tanya Stoyanova, Lora Topalova, Emil Gartchev and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Ina GioshevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Velichka StrijkovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-7807-4833
Regina Komsa-PenkovaDepartment of Biochemistry, Medical University-Pleven, 5800 Pleven, Bulgaria.ORCID 0000-0002-1349-9555
Sashka KrumovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-7412-8398
Ariana LangariInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Avgustina DanailovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Stefka G TanevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-6851-4516
Tanya StoyanovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Lora TopalovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Emil GartchevUniversity Obstetrics and Gynecology Hospital "Maichin Dom", 1431 Sofia, Bulgaria.
Galya GeorgievaDepartment of Biochemistry, Medical University-Pleven, 5800 Pleven, Bulgaria.
Svetla TodinovaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.ORCID 0000-0001-7108-051X
Bulgarian Academy of Sciences · BGMedical University Pleven · BGMaichin Dom · BG

Funding

Bulgarian National Science Fund KΠ-06-H21/4"Science and education for intelligence growth" within the European Regional Development Fund BG05M2OP001-1.002-0010-C03
6 · The paper itself

Abstract

Preeclampsia (PE) presents with maternal de novo hypertension and significant proteinuria and is one of the leading causes of maternal and perinatal morbidity and mortality with unknown etiology. The disease is associated with inflammatory vascular response and severe red blood cell (RBC) morphology changes. This study examined the nanoscopic morphological changes of RBCs from PE women versus normotensive healthy pregnant controls (PCs) and non-pregnant controls (NPCs) applying atomic force microscopy (AFM) imaging. The results revealed that the membrane of fresh PE RBCs differed significantly from healthy ones by the presence of invaginations and protrusions and an increased roughness value (R

Indexed as

Pre-EclampsiaErythrocyte MembraneErythrocytesFemaleHumansLongevityMicroscopy, Atomic ForcePregnancyatomic force microscopycell senescencemembrane impairmentmembrane roughnesspreeclampsiared blood cells

Identifiers

PMID37108270
PMCPMC10138579
OpenAlexW4365146714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.