Evidence map›Paper›PMID 37108235›Full record

ArticleInternational journal of molecular sciences2023

A Novel Hybrid Platform for Live/Dead Bacteria Accurate Sorting by On-Chip DEP Device.

Annarita di Toma, Giuseppe Brunetti, Maria Serena Chiriacò, Francesco Ferrara, Caterina Ciminelli

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  18. Tracking of Bacteriophage Predation onSensors (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annarita di TomaOptoelectronics Laboratory, Politecnico di Bari, Via E. Orabona 6, 70125 Bari, Italy.ORCID 0009-0008-8222-3756
Giuseppe BrunettiOptoelectronics Laboratory, Politecnico di Bari, Via E. Orabona 6, 70125 Bari, Italy.ORCID 0000-0002-6715-6777
Maria Serena ChiriacòCNR NANOTEC-Institute of Nanotechnology, Via per Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-7195-267X
Francesco FerraraCNR NANOTEC-Institute of Nanotechnology, Via per Monteroni, 73100 Lecce, Italy.
Caterina CiminelliOptoelectronics Laboratory, Politecnico di Bari, Via E. Orabona 6, 70125 Bari, Italy.ORCID 0000-0001-8724-016X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the World Health Organization (WHO) forecasts, Antimicrobial Resistance (AMR) will be the leading cause of death worldwide in the next decades. To prevent this phenomenon, rapid Antimicrobial Susceptibility Testing (AST) techniques are required to drive the selection of the most suitable antibiotic and its dosage. In this context, we propose an on-chip platform, based on a micromixer and a microfluidic channel, combined with a pattern of engineered electrodes to exploit the di-electrophoresis (DEP) effect. The role of the micromixer is to ensure the proper interaction of the antibiotic with the bacteria over a long time (≈1 h), and the DEP-based microfluidic channel enables the efficient sorting of live from dead bacteria. A sorting efficiency of more than 98%, with low power consumption (

Indexed as

Anti-Bacterial AgentsMicrofluidicsBacteriaElectrodesMicrobial Sensitivity TestsAnti-Bacterial Agentsantimicrobial susceptibility testingchip-scale platformdi-electrophoresisEscherichia colimicrofluidics

Identifiers

PMID37108235
PMCPMC10139405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.