Evidence map›Paper›PMID 37108234›Full record

ArticleInternational journal of molecular sciences2023

In Vitro and In Vivo Effects of the Combination of Polypurine Reverse Hoogsteen Hairpins against HER-2 and Trastuzumab in Breast Cancer Cells.

Ester López-Aguilar, Patricia Fernández-Nogueira, Gemma Fuster, Neus Carbó, Carlos J Ciudad, Véronique Noé

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ester López-AguilarDepartment of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0001-7343-9282
Patricia Fernández-NogueiraUnit of Biophysics and Bioengineering, Department of Biomedicine, School of Medicine and Health Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.
Gemma FusterDepartment of Biochemistry and Molecular Biomedicine, School of Biology, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0002-4501-2422
Neus CarbóDepartment of Biochemistry and Molecular Biomedicine, School of Biology, Universitat de Barcelona (UB), 08028 Barcelona, Spain.
Carlos J CiudadDepartment of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0002-7855-392X
Véronique NoéDepartment of Biochemistry and Physiology, School of Pharmacy and Food Sciences, Universitat de Barcelona (UB), 08028 Barcelona, Spain.ORCID 0000-0001-7937-8038

Funding

Ministerio de Ciencia e Innovación PID2021-122271OB-I00Ministerio de Ciencia e Innovación RTI2018-093901-B-I00
6 · The paper itself

Abstract

Therapeutic oligonucleotides are powerful tools for the inhibition of potential targets involved in cancer. We describe the effect of two Polypurine Reverse Hoogsteen (PPRH) hairpins directed against the

Indexed as

Breast NeoplasmsGenes, erbB-2Cell Line, TumorErb-b2 Receptor Tyrosine KinasesFemaleHumansMCF-7 CellsOncogenesRNA, MessengerTrastuzumabErb-b2 Receptor Tyrosine KinasesRNA, MessengerTrastuzumabbreast cancergene silencingHER-2PPRHtrastuzumab

Identifiers

PMID37108234
PMCPMC10139100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.