Evidence map›Paper›PMID 37108233›Full record

ArticleInternational journal of molecular sciences2023

Lipid-Sensing Receptor FFAR4 Modulates Pulmonary Epithelial Homeostasis following Immunogenic Exposures Independently of the FFAR4 Ligand Docosahexaenoic Acid (DHA).

Stefanie N Sveiven, Kyle Anesko, Joshua Morgan, Meera G Nair, Tara M Nordgren

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stefanie N SveivenDivision of Biomedical Sciences, School of Medicine, University of California-Riverside, Riverside, CA 92521, USA.
Kyle AneskoDivision of Biomedical Sciences, School of Medicine, University of California-Riverside, Riverside, CA 92521, USA.
Joshua MorganDepartment of Bioengineering, Bourns College of Engineering, University of California-Riverside, Riverside, CA 92521, USA.ORCID 0000-0001-8033-0285
Meera G NairDivision of Biomedical Sciences, School of Medicine, University of California-Riverside, Riverside, CA 92521, USA.ORCID 0000-0002-1807-5161
Tara M NordgrenDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0001-6398-8528
University of California, Riverside · USColorado State University · US

Funding

RELMalpha-expressing macrophages mediate host disease tolerance in mucosal infectionR01AI153195 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NAIR, MEERA GOH · 2020 to 2024
$3.5M
Omega-3 fatty acids induce macrophage IL-22 signaling to promote resolution of dust-induced lung inflammationR01HL158926 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI NORDGREN, TARA M · 2021 to 2025
$2.5M
The role of omega-3 fatty acids and bioactive lipid signaling in airway inflammation and resolution following organic dust exposuresR00ES025819 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NORDGREN, TARA M · 2017 to 2019
$747k
NHLBI NIH HHS R01 HL158926NIAID NIH HHS R01 AI153195NIEHS NIH HHS R00 ES025819NIEHS NIH HHS R00ES025819
6 · The paper itself

Abstract

The role of pulmonary free fatty acid receptor 4 (FFAR4) is not fully elucidated and we aimed to clarify the impact of FFAR4 on the pulmonary immune response and return to homeostasis. We employed a known high-risk human pulmonary immunogenic exposure to extracts of dust from swine confinement facilities (DE). WT and

Indexed as

Docosahexaenoic AcidsReceptors, G-Protein-CoupledAnimalsDietary SupplementsHumansInflammationLigandsLungMiceMice, KnockoutSwineDocosahexaenoic AcidsLigandsReceptors, G-Protein-CoupledDHAexposureFFAR4GPR120inflammationlung

Identifiers

PMID37108233
PMCPMC10138935
OpenAlexW4365146952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.