Evidence map›Paper›PMID 37108220›Full record

ArticleInternational journal of molecular sciences2023

Diplacone Isolated from

Myung-Ji Kang, Hyung Won Ryu, Eun Sol Oh, Yu Na Song, Yang Hoon Huh, Ji-Yoon Park, Seon Min Oh, Su-Yeon Lee, Yhun Jung Park, Doo-Young Kim and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Myung-Ji Kang *Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Hyung Won Ryu *Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.ORCID 0000-0001-5291-3942
Eun Sol OhNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Yu Na SongNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Yang Hoon HuhKorea Basic Science Institute, Cheongju 28119, Republic of Korea.
Ji-Yoon ParkNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Seon Min OhNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Su-Yeon LeeNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Yhun Jung ParkNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Doo-Young KimNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Hyunju RoDepartment of Biological Sciences, College of Bioscience and Biotechnology, Chungnam National University, Daejeon 34134, Republic of Korea.
Sung-Tae HongDepartments of Anatomy & Cell Biology, Department of Medical Science, College of Medicine, Chungnam National University, Daejeon 35015, Republic of Korea.ORCID 0000-0001-5981-4859
Su Ui LeeNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.ORCID 0000-0002-6455-5414
Dong-Oh MoonDepartment of Biology Education, Daegu University, 201 Daegudae-ro, Gyeongsan-si 38453, Republic of Korea.
Mun-Ock KimNatural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Korea Research Institute of Bioscience and Biotechnology · KRChungnam National University · KRDaegu University · KRKorea Basic Science Institute · KR

Funding

MSIT No. NRF-2020R1F1A1072032 and 2020R1C1C1011146
6 · The paper itself

Abstract

The recently defined type of cell death ferroptosis has garnered significant attention as a potential new approach to cancer treatment owing to its more immunogenic nature when compared with apoptosis. Ferroptosis is characterized by the depletion of glutathione (GSH)/glutathione peroxidase-4 (GPx4) and iron-dependent lipid peroxidation. Diplacone (DP), a geranylated flavonoid compound found in

Indexed as

FerroptosisCell DeathFlavanonesFruitGlutathioneHumansLipid PeroxidationMitochondrial Permeability Transition PoreMitochondrial Transmembrane Permeability-Driven NecrosisReactive Oxygen SpeciesdiplaconeFlavanonesGlutathioneMitochondrial Permeability Transition PoreReactive Oxygen Speciesdiplacone (DP)ferroptosismitochondria permeability transition (MPT)vacuolation

Identifiers

PMID37108220
PMCPMC10138418
OpenAlexW4367320934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.