Evidence map›Paper›PMID 37108134›Full record

ArticleInternational journal of molecular sciences2023

ZnO Nanorods Create a Hypoxic State with Induction of HIF-1 and EPAS1, Autophagy, and Mitophagy in Cancer and Non-Cancer Cells.

Michele Aventaggiato, Adele Preziosi, Hossein Cheraghi Bidsorkhi, Emily Schifano, Simone Vespa, Stefania Mardente, Alessandra Zicari, Daniela Uccelletti, Patrizia Mancini, Lavinia Vittoria Lotti and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Michele AventaggiatoDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0002-9466-0047
Adele PreziosiDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, P.le A. Moro,5, 00185 Rome, Italy.
Hossein Cheraghi BidsorkhiDepartment of Aerospace, Electrical and Energy Engineering, Sapienza University, Via Eudossiana 18, 00184 Rome, Italy.ORCID 0000-0001-7998-2999
Emily SchifanoDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, P.le A. Moro,5, 00185 Rome, Italy.
Simone VespaCenter for Advanced Studies and Technology, University "G. D'Annunzio" of Chieti-Pescara, Via Luigi Polacchi 11, 66100 Chieti, Italy.ORCID 0000-0001-6146-9302
Stefania MardenteDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0001-9032-9667
Alessandra ZicariDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.
Daniela UccellettiDepartment of Biology and Biotechnology "Charles Darwin", Sapienza University, P.le A. Moro,5, 00185 Rome, Italy.ORCID 0000-0001-6841-8129
Patrizia ManciniDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0003-0556-2056
Lavinia Vittoria LottiDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0002-5114-6953
Maria Sabrina SartoDepartment of Aerospace, Electrical and Energy Engineering, Sapienza University, Via Eudossiana 18, 00184 Rome, Italy.ORCID 0000-0002-8160-0803
Marco TafaniDepartment of Experimental Medicine, Sapienza University, Viale Regina Elena 324, 00161 Rome, Italy.ORCID 0000-0001-7128-810X
Sapienza University of Rome · ITUniversity of Chieti-Pescara · IT

Funding

Sapienza University of Rome Ateneo 2019
6 · The paper itself

Abstract

Nanomaterials are gaining increasing attention as innovative materials in medicine. Among nanomaterials, zinc oxide (ZnO) nanostructures are particularly appealing because of their opto-electrical, antimicrobial, and photochemical properties. Although ZnO is recognized as a safe material and the Zn ion (Zn

Indexed as

NeoplasmsZinc OxideAutophagyHumansHypoxiaHypoxia-Inducible Factor 1MCF-7 CellsMitophagyReactive Oxygen SpeciesHypoxia-Inducible Factor 1Reactive Oxygen SpeciesZinc OxideautophagycancerhypoxiamitophagynanomaterialsZnO nanorods

Identifiers

PMID37108134
PMCPMC10138614
OpenAlexW4363674462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.