Evidence map›Paper›PMID 37108112›Full record

ArticleInternational journal of molecular sciences2023

Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells.

Kuo-An Chu, Chang-Ching Yeh, Chun-Hsiang Hsu, Chien-Wei Hsu, Fu-Hsien Kuo, Pei-Jiun Tsai, Yu-Show Fu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kuo-An ChuDivision of Chest Medicine, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan.
Chang-Ching YehDepartment of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0003-0690-7503
Chun-Hsiang HsuDivision of Chest Medicine, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan.
Chien-Wei HsuDivision of Chest Medicine, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813414, Taiwan.
Fu-Hsien KuoInstitute of Anatomy and Cell Biology, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Pei-Jiun TsaiInstitute of Anatomy and Cell Biology, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Yu-Show FuDepartment of Anatomy and Cell Biology, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-4754-6006
National Yang Ming Chiao Tung University · TWKaohsiung Veterans General Hospital · TWNational Sun Yat-sen University · TW

Funding

Kaohsiung Veterans General Hospital VGHKS111-135 and VGHUST111-G3-1-1Ministry of Science and Technology MOST111-2321-B-A49-007
6 · The paper itself

Abstract

Pulmonary fibrosis (PF) is a progressive, non-reversible illness with various etiologies. Currently, effective treatments for fibrotic lungs are still lacking. Here, we compared the effectiveness of transplantation of human mesenchymal stem cells from umbilical cord Wharton's jelly (HUMSCs) versus those from adipose tissue (ADMSCs) in reversing pulmonary fibrosis in rats. Bleomycin 5 mg was intratracheally injected to establish a severe, stable, single left lung animal model with PF. On Day 21 post-BLM administration, one single transplantation of 2.5 × 10

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationPulmonary FibrosisWharton JellyAnimalsHumansRatsTransplantation, HeterologousUmbilical Cordadipose-derived mesenchymal stem cellspulmonary fibrosisumbilical mesenchymal stem cellsWharton’s jellyxenotransplantation

Identifiers

PMID37108112
PMCPMC10139084
OpenAlexW4362733038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.