Evidence map›Paper›PMID 37108063›Full record

ReviewInternational journal of molecular sciences2023

RNA-Dependent RNA Targeting by CRISPR-Cas Systems: Characterizations and Applications.

Natalia Gunitseva, Marta Evteeva, Anna Borisova, Maxim Patrushev, Fedor Subach

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Artificial Intelligence in CRISPR-Cas Systems: A Review of Tool Applications.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  7. Review
  8. A New RNA-Dependent Cas12g Nuclease.International journal of molecular sciences · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Natalia GunitsevaComplex of NBICS Technologies, National Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Marta EvteevaComplex of NBICS Technologies, National Research Center "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0003-1771-6382
Anna BorisovaComplex of NBICS Technologies, National Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Maxim PatrushevComplex of NBICS Technologies, National Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Fedor SubachComplex of NBICS Technologies, National Research Center "Kurchatov Institute", 123182 Moscow, Russia.ORCID 0000-0003-2720-7821
Kurchatov Institute · RU

Funding

Thematic plan of the National Research Center "Kurchatov Institute" Order № 91 from 20.01.2023the Ministry of Science and Higher Education of the Russian Federation 075-15-2021-1062
6 · The paper itself

Abstract

Genome editing technologies that are currently available and described have a fundamental impact on the development of molecular biology and medicine, industrial and agricultural biotechnology and other fields. However, genome editing based on detection and manipulation of the targeted RNA is a promising alternative to control the gene expression at the spatiotemporal transcriptomic level without complete elimination. The innovative CRISPR-Cas RNA-targeting systems changed the conception of biosensing systems and also allowed the RNA effectors to be used in various applications; for example, genomic editing, effective virus diagnostic tools, biomarkers, transcription regulations. In this review, we discussed the current state-of-the-art of specific CRISPR-Cas systems known to bind and cleave RNA substrates and summarized potential applications of the versatile RNA-targeting systems.

Indexed as

CRISPR-Cas SystemsRNABiotechnologyGene EditingRNAbiosensorsCas proteinsCRISPR/Cas-based detectiondiagnosticsRNA-targeting systemstrans-cleavage

Identifiers

PMID37108063
PMCPMC10138764
OpenAlexW4363675071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.