Evidence map›Paper›PMID 37108056›Full record

ReviewInternational journal of molecular sciences2023

Iron Deficiency and Iron Deficiency Anemia: Potential Risk Factors in Bone Loss.

Jiancheng Yang, Qingmei Li, Yan Feng, Yuhong Zeng

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
27.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Addition ofLife (Basel, Switzerland) · 2026
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  11. Animals : an open access journal from MDPI · 2026
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  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Association Between Gravidity and Anemia in Tabari Cohort Population: A Case-Control Study.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiancheng YangDepartment of Osteoporosis, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.ORCID 0000-0003-0008-9036
Qingmei LiDepartment of Osteoporosis, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Yan FengDepartment of Osteoporosis, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Yuhong ZengDepartment of Osteoporosis, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.
Xi'an Honghui Hospital · CN

Funding

National Natural Science Foundation of China 52107238Shaanxi Province Key R&D Projects 2023-YBSF-360
6 · The paper itself

Abstract

Iron is one of the essential mineral elements for the human body and this nutrient deficiency is a worldwide public health problem. Iron is essential in oxygen transport, participates in many enzyme systems in the body, and is an important trace element in maintaining basic cellular life activities. Iron also plays an important role in collagen synthesis and vitamin D metabolism. Therefore, decrease in intracellular iron can lead to disturbance in the activity and function of osteoblasts and osteoclasts, resulting in imbalance in bone homeostasis and ultimately bone loss. Indeed, iron deficiency, with or without anemia, leads to osteopenia or osteoporosis, which has been revealed by numerous clinical observations and animal studies. This review presents current knowledge on iron metabolism under iron deficiency states and the diagnosis and prevention of iron deficiency and iron deficiency anemia (IDA). With emphasis, studies related to iron deficiency and bone loss are discussed, and the potential mechanisms of iron deficiency leading to bone loss are analyzed. Finally, several measures to promote complete recovery and prevention of iron deficiency are listed to improve quality of life, including bone health.

Indexed as

Anemia, Iron-DeficiencyIron DeficienciesOsteoporosisAnimalsHumansIronQuality of LifeRisk FactorsIronanemiabone lossiron deficiencyiron metabolismosteoblastosteoclastosteoporosis

Identifiers

PMID37108056
PMCPMC10138976
OpenAlexW4363678673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.