Evidence map›Paper›PMID 37107593›Full record

ArticleGenes2023

SLC38A10 Deficiency in Mice Affects Plasma Levels of Threonine and Histidine in Males but Not in Females: A Preliminary Characterization Study of SLC38A10

Frida A Lindberg, Karin Nordenankar, Erica C Forsberg, Robert Fredriksson

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Frida A LindbergMolecular Neuropharmacology, Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden.ORCID 0000-0003-4665-3560
Karin NordenankarMolecular Neuropharmacology, Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden.
Erica C ForsbergMolecular Neuropharmacology, Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden.
Robert FredrikssonMolecular Neuropharmacology, Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden.
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solute carriers belong to the biggest group of transporters in the human genome, but more knowledge is needed to fully understand their function and possible role as therapeutic targets. SLC38A10, a poorly characterized solute carrier, is preliminary characterized here. By using a knockout mouse model, we studied the biological effects of SLC38A10 deficiency in vivo. We performed a transcriptomic analysis of the whole brain and found seven differentially expressed genes in SLC38A10-deficient mice (

Indexed as

HistidineThreonineAmino AcidsAnimalsFemaleHumansLiverMaleMembrane Transport ProteinsMiceAmino AcidsHistidineMembrane Transport ProteinsThreonineamino acid homeostasisgene expression analysisknockoutSNAT10solute carrier

Identifiers

PMID37107593
PMCPMC10138244
OpenAlexW4362465612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.