Evidence map›Paper›PMID 37107551›Full record

ArticleGenes2023

RNA-Seq Profiling between Commercial and Indigenous Iranian Chickens Highlights Differences in Innate Immune Gene Expression.

Ayeh Sadat Sadr, Mohammadreza Nassiri, Mostafa Ghaderi-Zefrehei, Maryam Heidari, Jacqueline Smith, Mustafa Muhaghegh Dolatabady

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Ayeh Sadat SadrSouth of Iran Aquaculture Research Institute, Iranian Fisheries Science Research Institute (IFSRI), Agricultural Research Education and Extension Organization (AREEO), Ahvaz 71867-37533, Iran.
Mohammadreza NassiriRecombinant Proteins Research Group, The Research Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad 91779-48974, Iran.
Mostafa Ghaderi-ZefreheiDepartment of Animal Science, Agricultural Faculty, Yasouj University, Yasouj 75918-74934, Iran.
Maryam HeidariDepartment of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 83111-84156, Iran.
Jacqueline SmithThe Roslin Institute and Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK.ORCID 0000-0002-2813-7872
Mustafa Muhaghegh DolatabadyDepartment of Animal Science, Agricultural Faculty, Yasouj University, Yasouj 75918-74934, Iran.
Yasouj University · IRAgricultural Research & Education Organization · IRIsfahan University of Technology · IRRoslin Institute · GBUNSW Sydney · AU

Funding

Biotechnology and Biological Sciences Research Council BBS/E/D/20002174Biotechnology and Biological Sciences Research Council BBS/E/D/30002276
6 · The paper itself

Abstract

The purpose of the current study was to examine transcriptomic-based profiling of differentially expressed innate immune genes between indigenous and commercial chickens. In order to compare the transcriptome profiles of the different chicken breeds, we extracted RNA from blood samples of the Isfahan indigenous chicken (as indigenous) and Ross broiler chicken (as commercial) breeds. RNA-Seq yielded totals of 36,763,939 and 31,545,002 reads for the indigenous and commercial breeds, respectively, with clean reads then aligned to the chicken reference genome (Galgal5). Overall, 1327 genes were significantly differentially expressed, of which 1013 genes were upregulated in the commercial versus the indigenous breed, while 314 were more highly expressed in the indigenous birds. Furthermore, our results demonstrated that the

Indexed as

ChickensTranscriptomeAnimalsImmunity, InnateIranRNA-Seqchickenscommercialgene expressionimmune genesindigenousRNA-Seqtranscriptome

Identifiers

PMID37107551
PMCPMC10138050
OpenAlexW4361007659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.