ReviewAntioxidants (Basel, Switzerland)2023
Impaired Melatonin Secretion, Oxidative Stress and Metabolic Syndrome in Night Shift Work.
Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- The 24/7 lifestyle and male hormonal health: how sleep deprivation and ultra-processed foods impact testosterone and reproduction.Reviews in endocrine & metabolic disorders · 2026Review
- The Inflammaging-Redox-InflammamiR Axis in Metabolic Aging: From Diagnostic Clusters to Integrated Risk Phenotypes.Biomolecules · 2026Review
- Circadian regulation of cardiovascular function: from physiology to clinical implications.Genome medicine · 2026Review
- Cell Signaling by Tryptophan Catabolism.Biochemistry · 2026Review
- Dynamic Oxidative States: Interplay of Aging, Metabolic Stress, and Circadian Rhythms in Modulating Stroke Severity.Antioxidants (Basel, Switzerland) · 2025Review
- Health Implications of Shift Work in Airline Pilots and Cabin Crew: A Narrative Review and Pilot Study Findings.Nutrients · 2025Review
- Night shift work and breast cancer: from etiopathology to precision risk analysis.NPJ breast cancer · 2025Review
- Oxidative Stress and Semen Quality Among Night- and Day-Shift Workers: A Cross-Sectional Study.Antioxidants (Basel, Switzerland) · 2025Article
- Associations Between Shift Work, Sociodemographic and Lifestyle Characteristics, Body Measurements, and MASLD.Life (Basel, Switzerland) · 2025Article
- Exploring Anti-Inflammatory Treatment as Upstream Therapy in the Management of Atrial Fibrillation.Journal of clinical medicine · 2025Review
- Article
- Association of shift work with metabolic dysfunction-associated fatty liver disease among subway workers.Frontiers in public health · 2025Article
- Association between exposure to terpene compounds and risk of metabolic syndrome: exploring the potential mediating role of inflammatory response.Frontiers in endocrinology · 2025Article
- Article
- Association between sleep traits and risk of colorectal cancer: a bidirectional Mendelian randomization study.Journal of gastrointestinal oncology · 2024Article
- Cytokine Storm: The Novel Mechanism for Sleep Deprivation-induced Multiple Organ Dysfunction Syndrome.Neuroscience bulletin · 2024Article
- To observe the clinical effect of lipoic acid combined with continuous positive airway pressure ventilation in treating obstructive sleep apnea-hypopnea syndrome and its effect on peripheral blood γ-aminobutyric acid and melatonin levels.Sleep & breathing = Schlaf & Atmung · 2024Article
- The relationship between oxidative balance score and circadian syndrome: evidence from the NHANES 2005-2018.Frontiers in endocrinology · 2024Article
- Meta-analysis of the Effect of Yogic Techniques on Melatonin Levels: Implications for Sleep Health.International journal of yogaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic syndrome has been associated in many studies with working in shifts. Even if the mechanistic details are not fully understood, forced sleep deprivation and exposure to light, as happens during night shifts, or irregular schedules with late or very early onset of the working program, lead to a sleep-wake rhythm misalignment, metabolic dysregulation and oxidative stress. The cyclic melatonin secretion is regulated by the hypothalamic suprachiasmatic nuclei and light exposure. At a central level, melatonin promotes sleep and inhibits wake-signals. Beside this role, melatonin acts as an antioxidant and influences the functionality of the cardiovascular system and of different metabolic processes. This review presents data about the influence of night shifts on melatonin secretion and oxidative stress. Assembling data from epidemiological, experimental and clinical studies contributes to a better understanding of the pathological links between chronodisruption and the metabolic syndrome related to working in shifts.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.