ArticleAntioxidants (Basel, Switzerland)2023
Mechanisms and Effect of Increased Physical Activity on General and Abdominal Obesity and Associated Metabolic Risk Factors in a Community with Very High Rates of General and Abdominal Obesity.
Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- The interplay between genetic and lifestyle obesity-related risk factors could be an important reason for the increasing epidemic of diabetes mellitus.Frontiers in endocrinology · 2026Article
- Incentivized walking improves chronic disease indicators: a short-term field intervention among an occupational population in Southeast China.Frontiers in public health · 2026Article
- Article
- Multimodal Associations of Modifiable Risk Factors on White Matter Injury: The SOL-INCA-MRI Study (HCHS/SOL).Stroke · 2025Article
- Effectiveness of the active senior program in preparing for physical deterioration and quality aging among pre-older adults in Prachin Buri Province, Thailand: A quasi-experimental study.Belitung nursing journal · 2025Article
- Exploring the Association between Socioeconomic Environment, Eating Habits and Level of Nutrition in Children of High School Age: A Part of National Survey.Children (Basel, Switzerland) · 2024Article
- Delay Discounting and BMI in Hypertensives: Serial Mediations of Self-Efficacy, Physical Activity and Sedentary Behavior.Journal of multidisciplinary healthcare · 2024Article
- Limitations and Future Directions for Research on Biomarkers and Endothelial Dysfunction in UAE Youth [Response to Letter].Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe growing prevalence of obesity and related type 2 diabetes is reaching epidemic proportions in the UAE. Physical inactivity is one of the possible factors linking obesity to diabetes and other related complications. However, the molecular mechanisms through which physical inactivity is contributing to increased obesity-related pathologies are not clear.
aimsto measure the effects of increased physical activity on obesity and related metabolic risk factors. MATERIALS AND
methodsWe investigated the effects of physical activity on body weight, waist circumference (WC) and metabolic risk factors in 965 community free-living Emirati subjects. Physical activity, dietary intake, antioxidant enzymes and markers of oxidative damage and inflammation were measured both at baseline and follow up. A validated questionnaire was used to assess occupation and leisure-related physical activity. We compared metabolic risk factors between subjects stratified by physical activity levels. The Cox proportional hazards analysis was used to determine the independent effects of increased physical activity on presence and absence of obesity, body weight and waist circumference (WC) change at follow up.
resultsA total of 965 community free-living subjects [801 (83%) females, mean (SD) age 39 ± 12 years] were recruited and followed up with for a period of 427 ± 223 days. Using WHO cut-of-points for body mass index (BMI), 284 (30%) subjects were overweight and 584 (62%) subjects were obese, compared to 69 (8%) at normal body weight. We found men to be more physically active than women at both leisure and work times. BMI, hip circumference, total body fat, HDL and inflammatory markers (us CRP, TNF) were significantly higher in female subjects, whilst fat free-mass, WC, blood pressure and HbA1c were higher in male subjects (
conclusionOur findings suggest that increased physical activity may decrease the risk of obesity and also mitigate the associated oxidative damage and inflammatory responses.
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