Evidence map›Paper›PMID 37106927›Full record

ArticleAnimals : an open access journal from MDPI2023

Masculinization of Red Tilapia (

Jakarwan Yostawonkul, Sirikorn Kitiyodom, Kittipat Supchukun, Nutthanit Thumrongsiri, Nattika Saengkrit, Komkiew Pinpimai, Amin Hajitou, Kim D Thompson, Kasem Rattanapinyopituk, Masashi Maita and 3 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Jakarwan YostawonkulThe International Graduate Course of Veterinary Science and Technology (VST), Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
Sirikorn KitiyodomWildlife, Exotic and Aquatic Animal Pathology Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-5180-6675
Kittipat SupchukunThe International Graduate Course of Veterinary Science and Technology (VST), Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
Nutthanit ThumrongsiriNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani 12120, Thailand.
Nattika SaengkritNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani 12120, Thailand.
Komkiew PinpimaiAquatic Resources Research Institute, Chulalongkorn University, Bangkok 10330, Thailand.
Amin HajitouCancer Phagotherapy, Department of Brain Sciences, Imperial College London, London W12 0NN, UK.
Kim D ThompsonMoredun Research Institute, Penicuik EH26 0PZ, UK.ORCID 0000-0003-3550-4842
Kasem RattanapinyopitukWildlife, Exotic and Aquatic Animal Pathology Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
Masashi MaitaLaboratory of Fish Health Management, Department of Marine Biosciences, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.
Manoj Tukaram KambleWildlife, Exotic and Aquatic Animal Pathology Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-7501-2151
Teerapong YataUnit of Biochemistry, Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
Nopadon PiraratWildlife, Exotic and Aquatic Animal Pathology Research Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
Chulalongkorn University · THNational Science and Technology Development Agency · THImperial College London · GBMoredun Research Institute · GBTokyo University of Marine Science and Technology · JP

Funding

The 90th Anniversary of Chulalongkorn University Fund (Ratchadaphiseksomphot Endowment Fund) N/AThe National Science and Technology Development Agency (NSTDA, Thailand) N/AThe Second Century Fund (C2F), Chulalongkorn University N/AThe Thailand Science Research and Innovation (TSRI) under the TRF Research Career Develop-ment Grant RSA 6280108
6 · The paper itself

Abstract

The aim of the present study was to optimize a masculinization platform for the production of all-male red tilapia fry by oral administration of 30 and 60 ppm of MT and alkyl polyglucoside nanostructured lipid carriers (APG-NLC) loaded with MT, respectively, for 14 and 21 days. The characterization, encapsulation efficiency and release kinetics of MT in lipid-based nanoparticles were assessed in vitro. The results showed that the MT-loaded nanoparticles were spherical, ranging from 80 to 125 nm in size, and had a negative charge with a narrow particle distribution. The APG-NLC loaded with MT provided higher physical stability and encapsulation efficacy than the NLC. The release rate constants of MT from MT-NLC and MT-APG-NLC were higher than those of free MT, which is insoluble in aqueous media. There was no significant difference in survival between the fish administered MT or the those fed orally with MT-APG-NLC fish. According to the logistic regression analysis, the sex reversal efficacy of MT-APG-NLC (30 ppm) and MT (60 ppm), resulted in significantly higher numbers of males after 21 days of treatment compared with the controls. The production cost of MT-APG-NLC (30 ppm) after 21 days of treatment was reduced by 32.9% compared with the conventional MT treatment group (60 ppm). In all the treatments, the length-weight relationship (LWR) showed negatively allomeric growth behavior (

Indexed as

17 alpha-methyltestosteronelipid-based nanoparticlesmasculinizationred tilapia (Oreochromis spp.)

Identifiers

PMID37106927
PMCPMC10135129
OpenAlexW4366091714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.