Evidence map›Paper›PMID 37106864›Full record

ArticleAnimals : an open access journal from MDPI2023

Transcriptomic and Proteomic Analyses Reveal New Insights into Regulatory Mechanisms of Strontium in Bovine Chondrocytes.

Fangyuan Zeng, Lan Li, Jiaqi Yang, Siqi Liu, Yang Yuan, Chenxu Zhao, Jianguo Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fangyuan ZengCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
Lan LiCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
Jiaqi YangCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
Siqi LiuCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
Yang YuanCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
Chenxu ZhaoCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.ORCID 0000-0003-0714-8510
Jianguo WangCollege of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.ORCID 0000-0003-2273-2539
Northwest A&F University · CN

Funding

National Natural Science Foundation of China 32102742National Natural Science Foundation of China 32273085
6 · The paper itself

Abstract

Strontium (Sr) is a trace element found mainly in bone, and it performs a dual action by promoting bone formation and inhibiting bone resorption. Sr has been used to evaluate the gastrointestinal calcium (Ca) absorption capacity of dairy cows due to the similar physicochemical properties of the two elements. However, the possible effects of Sr on dairy cows remain unclear. This study aimed to explore the potential regulatory mechanism of Sr in bovine chondrocytes by performing transcriptomic and proteomic analyses. A total of 111 genes (52 up-regulated and 59 down-regulated) were identified as significantly altered (1.2-fold change and

Indexed as

bovine chondrocyteproteomicsstrontiumtranscriptomic

Identifiers

PMID37106864
PMCPMC10135116
OpenAlexW4364375701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.