Evidence map›Paper›PMID 37106821›Full record

ArticleBiology2023

Development and Characterization of Inducible Astrocyte-Specific Aromatase Knockout Mice.

Jing Wang, Uday P Pratap, Yujiao Lu, Gangadhara R Sareddy, Rajeshwar R Tekmal, Ratna K Vadlamudi, Darrell W Brann

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jing WangDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Uday P PratapDepartment of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX 78229, USA.
Yujiao LuDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.
Gangadhara R SareddyDepartment of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX 78229, USA.ORCID 0000-0001-9977-3932
Rajeshwar R TekmalDepartment of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX 78229, USA.
Ratna K VadlamudiDepartment of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX 78229, USA.ORCID 0000-0003-2849-4076
Darrell W BrannDepartment of Neurosurgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-4480-8859
The University of Texas Health Science Center at San Antonio · USAugusta University · US

Funding

Brain Aromatase in Neurological Function and DiseaseR01NS088058 · NINDS · AUGUSTA UNIVERSITY · PI BRANN, DARRELL W, VADLAMUDI, RATNA K · 2015 to 2019
$1.8M
NINDS NIH HHS NS088058NINDS NIH HHS R01 NS088058
6 · The paper itself

Abstract

17β-estradiol (E2) is produced in the brain as a neurosteroid, in addition to being an endocrine signal in the periphery. The current animal models for studying brain-derived E

Indexed as

aromataseastrocytecerebral ischemiaestradiolmicroglianeuroestrogenneurosteroid

Identifiers

PMID37106821
PMCPMC10135694
OpenAlexW4366594033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.