ReviewBiology2023
Me, Myself and My Insula: An Oasis in the Forefront of Self-Consciousness.
Review in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04616287 (Self in Dementia With Lewy Bodies), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Self in Dementia With Lewy Bodies: a Behavioral and Multimodal Neuroimaging Study
Who cites it
19 citing papers in PubMed.
- Comparative insights into insula structure and function.Nature neuroscience · 2026Review
- Early reactivation of medial temporal lobe neurons during emergence from propofol anesthesia in neurosurgical patients.bioRxiv : the preprint server for biology · 2026Article
- Delineating In Vivo T1-Weighted Intensity Profiles Within the Human Insula Cortex Using 7-Tesla MRI.Human brain mapping · 2026Article
- Predictive processes linking sense of agency and fatigue: a novel allostatic framework.Frontiers in psychology · 2026Article
- Neurobiological mechanisms and treatment of empathic pain in nonsuicidal self-injury.Frontiers in psychiatry · 2026Review
- Apathy self-awareness and its neural correlates in Parkinson's Disease.NPJ Parkinson's disease · 2025Article
- Brain Tumors, AI and Psychiatry: Predicting Tumor-Associated Psychiatric Syndromes with Machine Learning and Biomarkers.International journal of molecular sciences · 2025Review
- Temporal characteristics of hemodynamic responses during active and passive hand movements in schizophrenia spectrum disorder.Schizophrenia (Heidelberg, Germany) · 2025Article
- Amygdala-insula response to neutral stimuli and the prospective prediction of anxiety sensitivity.Progress in neuro-psychopharmacology & biological psychiatry · 2025Article
- Direct interoceptive input to the insular cortex shapes learned feeding behavior.bioRxiv : the preprint server for biology · 2025Article
- Neural correlates of embodied and vibratory mechanisms associated with emotional prosody production.Social cognitive and affective neuroscience · 2025Article
- Neuroanatomical substrates of depression in dementia with Lewy bodies and Alzheimer's disease.GeroScience · 2024Article
- The insula: Leveraging cellular and systems-level research to better understand its roles in health and schizophrenia.Neuroscience and biobehavioral reviews · 2024Review
- Evolutionarily conserved neural responses to affective touch in monkeys transcend consciousness and change with age.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Who am I with my Lewy bodies? The insula as a core region of the self-concept networks.Alzheimer's research & therapy · 2024Article
- Neuroimaging of autobiographical memory in dementia with Lewy bodies: a story of insula.Brain communications · 2024Article
- Meeting the multidimensional self: fostering selfhood at the interface of Creative Arts Therapies and neuroscience.Frontiers in psychology · 2024Review
- Me, Myself, and I: Neural Activity for Self versus Other across Development.Children (Basel, Switzerland) · 2023Article
- Neurobiology of Behavior-Influences of Neuropsychiatric Disorders on Neurobiology and Behavior.Biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The insula is a multiconnected brain region that centralizes a wide range of information, from the most internal bodily states, such as interoception, to high-order processes, such as knowledge about oneself. Therefore, the insula would be a core region involved in the self networks. Over the past decades, the question of the self has been extensively explored, highlighting differences in the descriptions of the various components but also similarities in the global structure of the self. Indeed, most of the researchers consider that the self comprises a phenomenological part and a conceptual part, in the present moment or extending over time. However, the anatomical substrates of the self, and more specifically the link between the insula and the self, remain unclear. We conducted a narrative review to better understand the relationship between the insula and the self and how anatomical and functional damages to the insular cortex can impact the self in various conditions. Our work revealed that the insula is involved in the most primitive levels of the present self and could consequently impact the self extended in time, namely autobiographical memory. Across different pathologies, we propose that insular damage could engender a global collapse of the self.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.