Evidence map›Paper›PMID 37106767›Full record

ArticleBiology2023

Long-Term Effect of Diet Consistency on Mandibular Growth within Three Generations: A Longitudinal Cephalometric Study in Rats.

Ioannis A Tsolakis, Christos Verikokos, William Papaioannou, Konstantina-Eleni Alexiou, Zafeiroula Yfanti, Despoina Perrea, Apostolos I Tsolakis

Abstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. The Effect of Diabetes Mellitus on Mandibular Growth.Turkish journal of orthodontics · 2025
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ioannis A TsolakisDepartment of Orthodontics, School of Dentistry, Aristotle University of Thessaloniki, 54154 Thessaloniki, Greece.ORCID 0000-0002-5435-4889
Christos VerikokosSecond Department of Surgery, "Laikon Hospital", School of Medicine, National and Kapodistrian University of Athens, 10679 Athens, Greece.
William PapaioannouDepartment of Preventive & Community Dentistry, School of Dentistry, National and Kapodistrian University of Athens, 10679 Athens, Greece.ORCID 0000-0001-5146-4399
Konstantina-Eleni AlexiouDepartment of Oral Diagnosis & Radiology, School of Dentistry, National and Kapodistrian University of Athens, 10679 Athens, Greece.ORCID 0000-0001-6922-895X
Zafeiroula YfantiDepartment of Oral Diagnosis & Radiology, School of Dentistry, National and Kapodistrian University of Athens, 10679 Athens, Greece.ORCID 0000-0001-7817-5685
Despoina PerreaLaboratory of Experimental Surgery and Surgical Research, School of Medicine, National and Kapodistrian University of Athens, 10679 Athens, Greece.
Apostolos I TsolakisDepartment of Orthodontics, Case Western Reserve University School of Dental Medicine, Cleveland, OH 44106, USA.ORCID 0000-0003-3019-5438

Funding

National and Kapodistrian University of Athens 1405
6 · The paper itself

Abstract

backgroundThis study investigated the effect of diet consistency on mandibular growth of Wistar rats through three generations.

methodsA total breeding sample of 60 female and 8 male Wistar rats were used in this study. Measurements took place only on female animals. Twenty female Wistar rats at 30 days old and four male rats at 30 days old comprised the primary breeding sample of the first generation, and from these animals two different generations were reproduced. Lateral cephalometric X-rays were taken from all female rats at the age of 100 days. A total of 7 craniofacial landmarks were selected for the linear measurements, and 12 curves and 90 landmarks were selected for geometric morphometric analysis of the lateral X-rays. Bonferroni test and a permutation test were performed for the statistical analysis.

resultsMeans of measurements of all soft diet groups compared to hard diet groups were significantly smaller. According to linear measurements, there was a significant difference only between the first-generation soft diet with the third-generation soft diet group. According to geometric morphometric analysis, the statistical differences appeared on the condylar process and the angle of the mandible.

conclusionsThe soft diet could be responsible for less mandibular growth, and this information might be passing through generations.

Indexed as

condylar processgrowthhard dietmandiblesoft diet

Identifiers

PMID37106767
PMCPMC10136091

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.