ArticleBioengineering (Basel, Switzerland)2023
Multi-Objective Optimisation of a Novel Bypass Graft with a Spiral Ridge.
Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- FSI analysis of synthetic graft for coronary bypass flow: numerical optimization of geometric parameters.Physical and engineering sciences in medicine · 2026Article
- A novel vascular stent and insert concept to improve hemodynamics and support vascular health.Scientific reports · 2025Article
- Smoothed particle hydrodynamics based FSI simulation of the native and mechanical heart valves in a patient-specific aortic model.Scientific reports · 2024Article
- Enhancing the implantation of mechanical circulatory support devices using computational simulations.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The low long-term patency of bypass grafts is a major concern for cardiovascular treatments. Unfavourable haemodynamic conditions in the proximity of distal anastomosis are closely related to thrombus creation and lumen lesions. Modern graft designs address this unfavourable haemodynamic environment with the introduction of a helical component in the flow field, either by means of out-of-plane helicity graft geometry or a spiral ridge. While the latter has been found to lack in performance when compared to the out-of-plane helicity designs, recent findings support the idea that the existing spiral ridge grafts can be further improved in performance through optimising relevant design parameters. In the current study, robust multi-objective optimisation techniques are implemented, covering a wide range of possible designs coupled with proven and well validated computational fluid dynamics (CFD) algorithms. It is shown that the final set of suggested design parameters could significantly improve haemodynamic performance and therefore could be used to enhance the design of spiral ridge bypass grafts.
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Registered trials
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