ReviewBioengineering (Basel, Switzerland)2023
Analysis of Dental Enamel Remineralization: A Systematic Review of Technique Comparisons.
Review in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06905379 (Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial
Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- The role of probiotics in preventing dental caries: a systematic review of clinical evidence.Frontiers in oral health · 2025Pooled it
- Therapeutic Strategies and Genetic Implications for Periodontal Disease Management: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Comparative assessment of four treatments for post orthodontic white spot lesions over a 24-month period: a randomized controlled clinical trial.BMC oral health · 2026Trial
- Effect of remineralization after in office followed by home treatment of white spot lesions in children randomized controlled trial.Scientific reports · 2025Trial
- A Comparison of the Fluoride 'Paint- On' vs Tray Application Techniques for Enamel Remineralisation.International dental journal · 2024Trial
- Biomimetic Enamel Remineralization in Pediatric Dentistry: From Biological Principles to Clinical Evidence.Cureus · 2026Review
- Objective Measurement of Tooth Color Using Spectrophotometry and ICDAS: Quantifying CIELAB Color Changes Across Caries Severity.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026Article
- Methodological Heterogeneity in Profilometric Assessment of Experimentally Demineralized Enamel as a Model of White Spot Lesions: A Systematic Review.Journal of functional biomaterials · 2026Review
- The Role of Moringa oleifera in Caries Prevention and Enamel Remineralization.European journal of dentistry · 2026Article
- The Potential ofJournal of clinical medicine · 2026Review
- Evaluating the combined effect of a biomimetic organic matrix and bioinspired fluorapatite nanoparticles on initial caries lesions.RSC advances · 2026Article
- Fish bone and chitosan based nanogels in green dentistry: sustainable and eco-friendly biomimetic remineralizing agents for early enamel caries.BMC oral health · 2026Article
- Implant Surface Characteristics and Peri-Implant Outcomes: A Systematic Review of Clinical and Microbiological Evidence.Bioengineering (Basel, Switzerland) · 2026Review
- Dental Erosion Management: From Remineralization to Emerging Regenerative Approaches-A Narrative Review.Biomimetics (Basel, Switzerland) · 2026Review
- Influence of low viscosity resin infiltrant on the adhesion of orthodontic attachments.Dental press journal of orthodontics · 2026Article
- Effect of a Home Bleaching Gel Containing Chitosan and Theobromine on Tooth Surface Roughness, Microhardness, and Colour Change.Gels (Basel, Switzerland) · 2025Article
- Effectiveness of remineralizing dentifrices against caries lesions: A systematic approach.Journal of Taibah University Medical Sciences · 2025Review
- Eighty-Four-Month Clinical Outcomes of Autologous Dentin Graft Using Tooth TransformerJournal of functional biomaterials · 2025Article
- Fluoride in Dental Caries Prevention and Treatment: Mechanisms, Clinical Evidence, and Public Health Perspectives.Healthcare (Basel, Switzerland) · 2025Review
- Guidelines for Reducing the Adverse Effects of Shift Work on Nursing Staff: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The demineralization process conditions the structure of the enamel and begins with a superficial decalcification procedure that makes the enamel surface porous and gives it a chalky appearance. White spot lesions (WSLs) are the first clinical sign that can be appreciated before caries evolves into cavitated lesions. The years of research have led to the testing of several remineralization techniques. This study's objective is to investigate and assess the various methods for remineralizing enamel. The dental enamel remineralization techniques have been evaluated. A literature search on PubMed, Scopus, and Web of Science was performed. After screening, identification, and eligibility processes 17 papers were selected for the qualitative analysis. This systematic review identified several materials that, whether used singly or in combination, can be effective in the process of remineralizing enamel. All methods have a potential for remineralization when they come into contact with tooth enamel surfaces that have early-stage caries (white spot lesions). From the studies conducted in the test, all of the substances used to which fluoride has been added contribute to remineralization. It is believed that by developing and researching new remineralization techniques, this process might develop even more successfully.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.