Evidence map›Paper›PMID 37106649›Full record

ArticleBioengineering (Basel, Switzerland)2023

Assessment of the Remineralizing Potential of Biomimetic Materials on Early Artificial Caries Lesions after 28 Days: An In Vitro Study.

Vincenzo Tosco, Flavia Vitiello, Riccardo Monterubbianesi, Maria Laura Gatto, Giulia Orilisi, Paolo Mengucci, Angelo Putignano, Giovanna Orsini

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  8. Review
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  12. Mass Spectrometry Imaging of Biomaterials.Materials (Basel, Switzerland) · 2023
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vincenzo ToscoDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-3378-3844
Flavia VitielloDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-5152-7705
Riccardo MonterubbianesiDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-3419-665X
Maria Laura GattoDepartment of Industrial Engineering and Mathematical Sciences (DIISM), Università Politecnica delle Marche, 60131 Ancona, Italy.ORCID 0000-0002-1534-3140
Giulia OrilisiDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-2012-9923
Paolo MengucciDepartment of Materials, Environmental Sciences and Urban Planning (SIMAU) & UdR INSTM, Università Politecnica delle Marche, 60131 Ancona, Italy.ORCID 0000-0001-9049-8524
Angelo PutignanoDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.
Giovanna OrsiniDepartment of Clinical Sciences and Stomatology (DISCO), Università Politecnica delle Marche, 60126 Ancona, Italy.ORCID 0000-0002-2641-0695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the loss of mineral content in the enamel surface in early artificial lesions and to assess the remineralizing potential of different agents by means of SEM coupled with energy-dispersive X-ray analysis (EDX). The analysis was performed on the enamel of 36 molars divided into six equal groups, in which the experimental ones (3-6) were treated using remineralizing agents for a 28-day pH cycling protocol as follows: Group 1, sound enamel; Group 2, artificially demineralized enamel; Group 3, CPP-ACP treatment; Group 4, Zn-hydroxyapatite treatment; Group 5, NaF 5% treatment; and Group 6, F-ACP treatment. Surface morphologies and alterations in Ca/P ratio were evaluated using SEM-EDX and data underwent statistical analysis (

Indexed as

biomaterialsCPP-ACPdemineralizationearly enamel lesionenamel remineralizationF-ACPNaFnano-hydroxyapatiteSEM-EDX

Identifiers

PMID37106649
PMCPMC10135753

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.