Evidence map›Paper›PMID 37106642›Full record

ArticleBioengineering (Basel, Switzerland)2023

Metaverse and Healthcare: Machine Learning-Enabled Digital Twins of Cancer.

Omid Moztarzadeh, Mohammad Behdad Jamshidi, Saleh Sargolzaei, Alireza Jamshidi, Nasimeh Baghalipour, Mona Malekzadeh Moghani, Lukas Hauer

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Digital Twin Technology In Radiology.Journal of imaging informatics in medicine · 2026
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  10. NurseVerse: nursing in the metaverse era.Frontiers in medicine · 2025
    Review
  11. Article
  12. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omid MoztarzadehDepartment of Stomatology, University Hospital Pilsen, Faculty of Medicine in Pilsen, Charles University, 32300 Pilsen, Czech Republic.ORCID 0000-0002-4768-2382
Mohammad Behdad JamshidiFaculty of Electrical Engineering, University of West Bohemia, 30100 Pilsen, Czech Republic.ORCID 0000-0002-5312-6497
Saleh SargolzaeiDepartment of Computer Engineering, Mashhad Branch, Islamic Azad University, Mashhad 9187147578, Iran.ORCID 0009-0006-1471-3337
Alireza JamshidiDentistry School, Babol University of Medical Sciences, Babol 4717647745, Iran.ORCID 0000-0003-1736-5607
Nasimeh BaghalipourDepartment of Stomatology, University Hospital Pilsen, Faculty of Medicine in Pilsen, Charles University, 32300 Pilsen, Czech Republic.ORCID 0000-0002-5961-5806
Mona Malekzadeh MoghaniDepartment of Radiation Oncology, Medical School, Shahid Beheshti, University of Medical Sciences, Teheran 1985717443, Iran.
Lukas HauerDepartment of Stomatology, University Hospital Pilsen, Faculty of Medicine in Pilsen, Charles University, 32300 Pilsen, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical digital twins, which represent medical assets, play a crucial role in connecting the physical world to the metaverse, enabling patients to access virtual medical services and experience immersive interactions with the real world. One serious disease that can be diagnosed and treated using this technology is cancer. However, the digitalization of such diseases for use in the metaverse is a highly complex process. To address this, this study aims to use machine learning (ML) techniques to create real-time and reliable digital twins of cancer for diagnostic and therapeutic purposes. The study focuses on four classical ML techniques that are simple and fast for medical specialists without extensive Artificial Intelligence (AI) knowledge, and meet the requirements of the Internet of Medical Things (IoMT) in terms of latency and cost. The case study focuses on breast cancer (BC), the second most prevalent form of cancer worldwide. The study also presents a comprehensive conceptual framework to illustrate the process of creating digital twins of cancer, and demonstrates the feasibility and reliability of these digital twins in monitoring, diagnosing, and predicting medical parameters.

Indexed as

artificial intelligencebreast cancercancerdigital twinshealthcaremachine learningmetaverse

Identifiers

PMID37106642
PMCPMC10136137

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.