Evidence map›Paper›PMID 37106364›Full record

ReviewParasites & vectors2023

Heartworm adulticide treatment: a tropical perspective.

Filipe Dantas-Torres, Jennifer Ketzis, Gabriela Pérez Tort, Andrei Daniel Mihalca, Gad Baneth, Domenico Otranto, Malaika Watanabe, Bui Khanh Linh, Tawin Inpankaew, Pablo Borrás and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Parasites & vectors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Presence ofCurrent research in parasitology & vector-borne diseases · 2026
    Article
  8. Article
  9. A meta-analysis onParasitology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. DetectingPathogens (Basel, Switzerland) · 2024
    Review
  14. Control of companion animal parasites and impact on One Health.One health (Amsterdam, Netherlands) · 2024
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 15 institutions in 13 countries.

Filipe Dantas-TorresInstituto Aggeu Magalhães, Fundação Oswaldo Cruz (Fiocruz), Recife, Pernambuco, Brazil. filipe.torres@fiocruz.br.
Jennifer KetzisRoss University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis.
Gabriela Pérez TortUniversity of Buenos Aires and Virreyes Veterinary Hospital, Buenos Aires, Argentina.
Andrei Daniel MihalcaUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Cluj-Napoca, Romania.
Gad BanethThe Hebrew University of Jerusalem, Rehovot, Israel.
Domenico OtrantoUniversity of Bari, Valenzano, Bari, Italy.
Malaika WatanabeUniversity Putra Malaysia, Serdang, Selangor, Malaysia.
Bui Khanh LinhVietnam National University of Agriculture, Hanoi, Vietnam.
Tawin InpankaewKasetsart University, Bangkok, Thailand.
Pablo BorrásAdministración Nacional de Laboratorios e Institutos de Salud Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Sangaran ArumugamMadras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India.
Barend Louis PenzhornUniversity of Pretoria, Pretoria, South Africa.
Adrian Patalinghug YbañezCebu Technological University, Cebu, Philippines.
Peter IrwinMurdoch University, Perth, Australia.
Rebecca J TraubMelbourne Veterinary School, University of Melbourne, Parkville, VIC, Australia.
Administración Nacional de Laboratorios e Institutos de Salud · ARCebu Technological University · PHFundação Oswaldo Cruz · BRHebrew University of Jerusalem · ILKasetsart University · THMurdoch University · AURoss University School of Veterinary Medicine · KNTamil Nadu Veterinary and Animal Sciences University · INUniversiti Putra Malaysia · MYUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · ROUniversity of Bari Aldo Moro · ITUniversity of Buenos Aires · ARUniversity of Melbourne · AUUniversity of Pretoria · ZAVietnam National University of Agriculture · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dirofilaria immitis (the canine heartworm) is widespread in the tropics, with prevalence surpassing 30% in high-risk areas. In addition to the suitable climatic conditions that favour mosquito abundance and filarial larva development, there is low compliance with the recommended year-round use of preventives in these transmission hotspots. This represents a major concern, considering that melarsomine (first-line heartworm adulticide) is unavailable in several tropical countries, resulting in the so-called slow-kill protocol being the only available adulticide treatment option. In this article, the members of TroCCAP (Tropical Council for Companion Animal Parasites) review the current distribution of heartworm in the tropics and the availability of melarsomine, and discuss alternatives for the management of heartworm infections in dogs.

Indexed as

Dirofilaria immitisDirofilariasisDog DiseasesFilaricidesAnimalsArsenicalsDogsTriazinesArsenicalsFilaricidesmelarsomineTriazinesDirofilaria immitisDoxycyclineIvermectinMelarsomineMosquitoesMoxidectinOne healthPrevention

Identifiers

PMID37106364
PMCPMC10141906
OpenAlexW4367172481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.