Evidence map›Paper›PMID 37106335›Full record

ArticleBMC gastroenterology2023

Peripheral blood T-lymphocyte subsets are potential biomarkers of disease severity and clinical outcomes in patients with ulcerative colitis: a retrospective study.

Bailu Geng, Xueli Ding, Xiaoyu Li, Hua Liu, Wenjun Zhao, Haihong Gong, Zibin Tian, Jing Guo

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bailu GengDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China.
Xueli DingDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China.
Xiaoyu LiDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China.
Hua LiuDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China.
Wenjun ZhaoDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China.
Haihong GongDepartment of Respiratory and Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, China.
Zibin TianDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China. tianzb@qdu.edu.cn.
Jing GuoDepartment of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, 266003, Shandong, China. guojing0207@126.com.
Affiliated Hospital of Qingdao University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUlcerative colitis (UC) is considered an immune-mediated disease. The disorder of T-lymphocyte subsets plays an important role in the pathogenesis of UC. The aim of this study was to evaluate the significance of peripheral blood T-lymphocyte subsets in assessing disease severity and predicting clinical outcomes in UC patients.

methodsThe retrospective case-control study was performed in 116 UC patients with active disease and 90 healthy controls (HC). The UC patients included were followed up for 180 days. Analyses of t-test, Spearman's correlation coefficient, multivariable Cox regression analysis, receiver operating characteristic (ROC) curves and cumulative survival analysis were done.

resultsThe UC patients had lower proportions of CD4

conclusionsThe combination of CD3

Indexed as

Colitis, UlcerativeBiomarkersCase-Control StudiesHLA-DR AntigensHumansPatient AcuityRetrospective StudiesT-Lymphocyte SubsetsBiomarkersHLA-DR AntigensBiomarkersPrognosisT-lymphocyte subsetsUlcerative colitis

Identifiers

PMID37106335
PMCPMC10134527
OpenAlexW4367183958

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.