Trial reportBMC anesthesiology2023
Comparing ultrasound-guided modified thoracoabdominal nerves block through perichondrial approach with oblique subcostal transversus abdominis plane block for patients undergoing laparoscopic cholecystectomy: a randomized, controlled trial.
Trial report in BMC anesthesiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05108129 (Ultrasound-guided Modified Thoracoabdominal Nerves Block Through Perichondrial Approach), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound-guided Modified Thoracoabdominal Nerves Block Through Perichondrial Approach(M-TAPA)Versus Oblique Subcostal Transversus Abdominis Plane Block(OSTAP) for Postoperative Analgesia of Patients Undergoing Laparoscopic Cholecystectomy
Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Modified Thoracoabdominal Nerves Block Through the Perichondrial Approach vs Subcostal Transversus Abdominis Plane Block for Postoperative Recovery After Laparoscopic Cholecystectomy: A Prospective, Randomized Clinical Trial.Medical science monitor : international medical journal of experimental and clinical research · 2026Trial
- Efficacy of ultrasound-guided recto-intercostal fascial plane block for postoperative analgesia in laparoscopic cholecystectomy: a randomized controlled trial.Surgical endoscopy · 2026Trial
- Anterior Quadratus lumborum block versus modified perichondrial thoracoabdominal nerve block (m-TAPA) for postoperative analgesia following laparoscopic cholecystectomy: a randomized controlled trial.BMC anesthesiology · 2025Trial
- Analgesic efficacy of the external oblique intercostal fascial plane block on postoperative acute pain in laparoscopic sleeve gastrectomy: a randomized controlled trial.Korean journal of anesthesiology · 2025Trial
- Thoracoabdominal nerves block through the perichondrial approach: a narrative review.Korean journal of anesthesiology · 2026Review
- Ultrasound identification of absent rectus abdominis muscle after omphalocele repair altered regional anesthesia strategy in pediatric cardiac surgery: a case report.JA clinical reports · 2026Article
- Regional Anesthesia to Save the Day for Kids: A Narrative Review of Literature About the Blocks to Know for Common Pediatric Surgeries.Medicina (Kaunas, Lithuania) · 2026Review
- Comparison of the Postoperative Analgesic Effects of TAP and M-TAPA Blocks in Laparoscopic Appendectomy: A Pilot Randomized Controlled Trial.Journal of pain research · 2026Article
- Analgesic efficacy of ultrasound-guided modified thoracoabdominal nerve block in paediatric upper abdominal surgery: A randomised controlled trial.Indian journal of anaesthesia · 2025Article
- Bilateral Modified Thoracoabdominal Nerve Block Through a Perichondrial Approach in Patients Undergoing Major Abdominal Surgery: A Randomized Single-Blind Controlled Trial.Turkish journal of anaesthesiology and reanimation · 2025Article
- A hidden ally in laparoscopic cholecystectomy: quadratus lumborum block and the quest for pain-free recovery.Frontiers in surgery · 2025Review
- Modified thoracoabdominal nerves block through perichondrial approach for surgical patients: a scoping review.BMC anesthesiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic cholecystectomy(LC) causes significant postoperative pain. Oblique subcostal transversus abdominis plane(OSTAP) block was described for postoperative analgesia, especially for upper abdominal surgeries. Modified thoracoabdominal nerves block through perichondrial approach(M-TAPA) block is a new technique defined by the modification of the thoracoabdominal nerves through perichondrial approach (TAPA) block, in which local anesthetics are delivered only to the underside of the perichondral surface. The primary aim of this study was to evaluate the effect of M-TAPA and OSTAP blocks as part of multimodal analgesia on postoperative opioid consumption in patients undergoing LC.
methodThe present study was designed as a randomized, controlled, prospective study. Seventy-six adult patients undergoing LC were randomly assigned to receive either bilaterally M-TAPA or OSTAP block after the induction of anesthesia and before surgery using bupivacaine 0.25%, 25 ml. The primary outcome was assessed as postoperative 24 h opioid consumption, between groups were compared. Secondary outcomes were Numerical Rational scale(NRS) scores, time to first opioid analgesia, patient recovery, using the Quality of Recovery-15 (QoR-15) scale, nausea and vomiting, sedation score, metoclopramide consumption, and evaluating the analgesic range of dermatome.
resultsThe mean tramadol consumption at the postoperative 24th hour was higher in the group OSTAP than in group M-TAPA (P = 0.047). NRS movement score at 12th hour was statistically significantly lower in group M-TAPA than in group OSTAP (P = 0.044). Dermatomes showed intense sensory analgesia between T7-11 in both groups, and it was determined that there was proportionally more involvement in the group M-TAPA. There were no differences between the groups in terms of other results.
conclusionsAfter the LC surgery, ultrasound-guided M-TAPA block effectively reduced opioid consumption, postoperative pain, and QoR-15 scores similar to OSTAP block. CLINICAL
trial registrationThe study was registered prospectively at clinicaltrials.gov (trial ID: NCT05108129 on 4/11/2021).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.