Observational studyObesity surgery2023
The Performance of Opioid-Free Anesthesia for Bariatric Surgery in Clinical Practice.
Observational study in Obesity surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Comparison of Opioid-Free Versions of Total Intravenous Anesthesia and Inhalational Anesthesia in Bariatric Surgery: A Randomized Controlled Trial.Obesity surgery · 2026Trial
- Esketamine-led opioid-free anaesthesia reduces postoperative pulmonary complications in bariatric surgery patients: a prospective randomized controlled trial.BMC anesthesiology · 2026Trial
- Opioid-free anesthesia in bariatric surgery: a prospective randomized controlled trial.European journal of medical research · 2025Trial
- Comparison between multimodal and intraoperative opioid free anesthesia for laparoscopic sleeve gastrectomy: a prospective, randomized study.Scientific reports · 2023Trial
- Effect of Opioid-Sparing Anesthesia on Postoperative Nausea and Vomiting After Breast Surgery: A Single-Center Randomized Controlled Trial.Journal of clinical medicine · 2026Article
- Effectiveness of a stepwise implementation of enhanced recovery after bariatric surgery: our experience.Updates in surgery · 2025Observational
- Chronic Post-Surgical Pain After Laparoscopic Sleeve Gastrectomy: Is the Opioid-Free Anesthesia Superior? A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Response to "The Performance of Opioid-Free Anesthesia for Bariatric Surgery in Clinical Practice".Obesity surgery · 2025Article
- The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery.Obesity surgery · 2025Article
- Comparison between opioid-based anaesthesia technique and opioid-free anaesthesia technique in patients undergoing laparotomy for gynaecological malignancy: A randomised controlled trial.Indian journal of anaesthesia · 2025Article
- Opioid-free versus opioid-based anesthesia in laparoscopic sleeve gastrectomy: a single-center, randomized, controlled trial.Perioperative medicine (London, England) · 2025Article
- Correct understanding and intervention of postoperative nausea and vomiting can provide reference for clinical practice.World journal of gastrointestinal surgery · 2024Article
- Review
- Implementation of updated enhanced recovery after bariatric surgery guidelines: adapted protocol in a single tertiary center.Updates in surgery · 2024Observational
- Opioid-Free Anesthesia in Bariatric Surgery: Is It the One and Only? A Comprehensive Review of the Current Literature.Healthcare (Basel, Switzerland) · 2024Review
- [Opioid-free anesthesia : Wrong track or meaningful exit from the era of opioid-based analgesia?]Die Anaesthesiologie · 2024Review
- Successful Anesthetic Management for Obese Patients with Interstitial Lung Disease Undergoing Laparoscopic Sleeve Gastrectomy: A Bridge to Improved Lung Transplant Eligibility.The American journal of case reports · 2024Article
- Letter to the Editor Regarding "The Performance of Opioid-Free Anesthesia for Bariatric Surgery in Clinical Practice".Obesity surgery · 2024Article
- Effect of opioid-freeBJA open · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOpioid-free anesthesia (OFA) is an alternative to conventional opioid-based anesthesia (OBA) in patients undergoing bariatric surgery. Several small studies and a meta-analysis have suggested advantages of OFA for bariatric surgery, but current evidence is still contradictory, and a universally accepted concept has not yet been established. The purpose of this study was to determine whether patients undergoing bariatric surgery experience less postoperative pain and better postoperative recovery when anesthetized with an OFA regimen than with an OBA regimen. MATERIALS AND
methodsThis prospective observational cohort study, conducted between October 2020 and July 2021, compared patients receiving OFA with patients receiving OBA. Patients were visited 24 and 48 h after the surgical procedure and asked about their postoperative pain using the visual analogue scale (VAS). Additionally, the quality of recovery-40 questionnaire (QoR-40) and the postoperative opioid requirements were recorded.
resultsNinety-nine patients were included and analyzed in this study (OFA: N = 50; OBA: N = 49). The OFA cohort exhibited less postoperative pain than the OBA cohort within 24 h (VAS median [interquartile range (IQR)]: 2.2 [1-4.4] vs. 4.1 [2-6.5]; P ≤ 0.001) and 48 h (VAS median [IQR]: 1.9 [0.4-4.1] vs. 3.1 [1.4-5.8]; P ≤ 0.001) postoperatively. Additionally, the OFA cohort had higher QoR-40 scores and required less opioid therapy postoperatively.
conclusionBased on our results the use of OFA for bariatric surgery results in less pain, reduced opioid requirements, and improved postoperative recovery-adding additional evidence regarding the use of OFA in everyday clinical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.