ArticleIntensive care medicine experimental2023
Comparison of cardiac index measurements in intensive care patients using continuous wave vs. pulsed wave echo-Doppler compared to pulse contour cardiac output.
Article in Intensive care medicine experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.
- Levosimendan vs. Milrinone in cardiac surgery: A GRADE-assessed systematic review and meta-analysis.European journal of clinical pharmacology · 2026Pooled it
- Analysis of risk factors of low cardiac output syndrome after pericardiectomy for tuberculous constrictive pericarditis: A retrospective study.Indian heart journalArticle
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCardiac index (CI) assessments are commonly used in critical care to define shock aetiology and guide resuscitation. Echocardiographic assessment is non-invasive and has high levels of agreement with thermodilution assessment of CI. CI assessment is derived from the velocity time integral (VTI) assessed using pulsed wave (PW) doppler at the level of the left ventricular outflow tract divided by body mass index. Continuous wave (CW) doppler through the aortic valve offers an alternative means to assess VTI and may offer better assessment at high velocities.
methodsWe performed a single centre, prospective, observational study in a 15-bed intensive care unit in a busy district general hospital. Patients had simultaneous measurements of cardiac index by Pulse Contour Cardiac Output (PiCCO) (thermodilution), transthoracic echocardiographic PW-VTI and CW-VTI. Mean differences were measured with Bland-Altman limits of agreement and percentage error (PE) calculations.
resultsData were collected on 52 patients. 71% were supported with noradrenaline with or without additional inotropic or vasopressor agents. Mean CIs were: CW-VTI 2.7 L/min/m
conclusionsCI derived from both CW-VTI and PW-VTI methods underestimate CI compared to PiCCO, with the CW-VTI method having closer values overall to PiCCO. CW-VTI may offer a more accurate assessment of CI. If using Critchley's PE cutoff of 30%, none of the doppler methods may accurately reflect the actual cardiac index.
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