Evidence map›Paper›PMID 37106192›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Measurement of Forces for Trans-Endocytosis at Dorsal and Ventral Sides of the Cell.

Seungman Park, Yun Chen

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Seungman ParkDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA.
Yun ChenDepartment of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, USA. yun.chen@jhu.edu.
Johns Hopkins University · USNanoBio (United States) · US

Funding

Characterization of relation between tissue viscoelasticity and tumor progression in aging tissuesK25AG070286 · NIA · UNIVERSITY OF NEVADA LAS VEGAS · PI PARK, SEUNGMAN · 2021 to 2025
$734k
NIA NIH HHS K25 AG070286
6 · The paper itself

Abstract

Trans-endocytosis is a force dependent process during which surface molecules expressed on one cell but bound to their receptors on another cell are displaced and internalized by the cell expressing the receptors. The efficiency of trans-endocytosis is associated with the capacity of force generation of the cell. Here we present three different methods to measure the forces generated during trans-endocytosis using tension gauge tether (TGT), micropillar arrays, and microfluidic devices. The TGT method detects forces generated at the single-molecule (nm) scale and the other two methods detect forces with the resolution at the micron scale. Trans-endocytic forces transmitted via the receptors at dorsal side of the cell can be determined using the TGT and the microfluidic-based methods, while forces transmitted at the ventral side can be determined using the micropillar-based method.

Indexed as

EndocytosisMechanical PhenomenaForce measurementMicrofluidicsMicropillar arraysTension gauge tetherTrans-endocytosis

Identifiers

PMID37106192
PMCPMC10316711
OpenAlexW4367281671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.