ArticleNature human behaviour2023
Participation bias in the UK Biobank distorts genetic associations and downstream analyses.
Article in Nature human behaviour, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 264 papers, 7 of them syntheses that pooled it.
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Who cites it
264 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Socioeconomic position, genetic susceptibility, and epigenetic profiles in obesity across the life course: a systematic review.International journal of obesity (2005) · 2026Pooled it
- Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort.PLoS genetics · 2026Pooled it
- Gene-environment interplay explaining individual variation in BMI outcomes: a systematic review and meta-analysis of studies using polygenic indices.International journal of obesity (2005) · 2026Pooled it
- Discovery of obesity genes through cross-ancestry analysis.Nature communications · 2025Pooled it
- Large-scale genome-wide analyses of stuttering.Nature genetics · 2025Pooled it
- Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.Translational psychiatry · 2025Pooled it
- A meta-analysis and polygenic score study identifies novel genetic markers for waist-hip ratio in African populations.Obesity (Silver Spring, Md.) · 2024Pooled it
- Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants.Nature genetics · 2026Article
- Design and model choices shape inference of age-varying genetic effects on complex traits.Nature aging · 2026Article
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- Novel associations of Claudin gene variants with kidney stone disease.Clinical kidney journal · 2026Article
- Heritability and social interaction in labor market outcomes: Evidence from the population of twins in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Childhood Correlates of Genetic Propensity to Personality Traits.medRxiv : the preprint server for health sciences · 2026Article
- Androgens mediate sexual dimorphism in Pilarowski-Bjornsson syndrome.American journal of human genetics · 2026Article
- Analysis of rare coding variants in schizophrenia-associated genes and generalised cognition in the UK Biobank.Molecular psychiatry · 2026Article
- Immune markers mediate genetic relationships between immune diseases and psychiatric disorders.PLoS genetics · 2026Article
- Delivery mode and maternal health conditions before and after childbirth: A population-based cohort study from Estonia.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Loneliness, Genetic Susceptibility, Brain Structure, and the Risk of Schizophrenia: A Large Prospective Study.Schizophrenia bulletin · 2026Article
- Determinants of functional burden pleiotropy and gene dosage responses across human traits.Nature communications · 2026Article
- Maternal genetic liability to autism spectrum disorders and pregnancy outcomes.Archives of women's mental health · 2026Article
204 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
Abstract
While volunteer-based studies such as the UK Biobank have become the cornerstone of genetic epidemiology, the participating individuals are rarely representative of their target population. To evaluate the impact of selective participation, here we derived UK Biobank participation probabilities on the basis of 14 variables harmonized across the UK Biobank and a representative sample. We then conducted weighted genome-wide association analyses on 19 traits. Comparing the output from weighted genome-wide association analyses (n
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