Evidence map›Paper›PMID 37105834›Full record

ReviewSeminars in immunology2023

Mechanisms of climate change and related air pollution on the immune system leading to allergic disease and asthma.

Vanitha Sampath, Juan Aguilera, Mary Prunicki, Kari C Nadeau

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Wildfire and asthma - The prospective interventions.The World Allergy Organization journal · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Positive rates ofFrontiers in microbiology · 2025
    Article
  16. Article
  17. Asthma Pathogenesis: Phenotypes, Therapies, and Gaps: Summary of the Aspen Lung Conference 2023.American journal of respiratory cell and molecular biology · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Vanitha SampathSean N. Parker Center for Allergy and Asthma Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: vsampath@stanford.edu.
Juan AguileraCenter for Community Health Impact, The University of Texas Health Science Center at Houston School of Public Health, El Paso, Texas, USA.
Mary PrunickiSean N. Parker Center for Allergy and Asthma Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Kari C NadeauDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Harvard University · USStanford Medicine · USStanford University · USThe University of Texas Health Science Center at Houston · US

Funding

Scientific Human Biomarker Exposure Monitoring Core (HEMC) for the Air pollution disrupts Inflammasome Regulation in HEart And Lung Total Health (AIRHEALTH) StudyP01HL152953 · NHLBI · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2021 to 2025
$9.8M
Fresno Asthmatic Children's Environment Study (FACES)R01HL081521 · NHLBI · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAGER, IRA B · 2006 to 2010
$3.8M
Immune Tolerance Dysfunction in Pregnancy due to Ambient Air Pollution ExposureR01ES032253 · NIEHS · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2020 to 2024
$2.2M
NHLBI NIH HHS P01 HL152953NHLBI NIH HHS R01 HL081521NIEHS NIH HHS R01 ES032253
6 · The paper itself

Abstract

Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent and intense heat and cold waves, wildfires, floods, drought, altered rainfall patterns, hurricanes, thunderstorms, air pollution, and windstorms. These extreme weather events have direct and indirect effects on the immune system, leading to allergic disease due to exposure to pollen, molds, and other environmental pollutants. In this review, we will focus on immune mechanisms associated with allergy and asthma-related health risks induced by climate change events. We will review current understanding of the molecular and cellular mechanisms by which the changing environment mediates these effects.

Indexed as

Air PollutionAsthmaClimate ChangeHypersensitivityAnimalsDisastersHumansImmune SystemAllergyAsthmaClimate changePollenPollutionWildfire

Identifiers

PMID37105834
PMCPMC10275624
OpenAlexW4366977139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.