Evidence map›Paper›PMID 37105721›Full record

ArticleJournal of neurointerventional surgery2024

Cost-utility of direct transfer to angiography suite (DTAS) bypassing conventional imaging for patients with acute ischemic stroke in Spain: results from the ANGIOCAT trial.

Manuel Requena, Henri Vanden Bavière, Sanjay Verma, Carin Gerrits, Tom Kokhuis, Alejandro Tomasello, Carlos A Molina, Marc Ribo

Abstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Direct to hybrid CT-angiosuite (Nexaris) reduces treatment time for stroke thrombectomy (Direct-ST): A prospective simulation study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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  4. Medium vessel occlusions in the drip-and-ship model: Clinical vs. hub CTP-supported decision making.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manuel RequenaDepartment of Neurology, Vall d'Hebron University Hospital, Stroke Unit, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5671-6484
Henri Vanden BavièreChief Medical Office, Philips, Amsterdam, The Netherlands.
Sanjay VermaChief Medical Office, Philips, Amsterdam, The Netherlands.
Carin GerritsImage Guided Therapy, Philips Healthcare, Best, The Netherlands.
Tom KokhuisImage Guided Therapy, Philips Healthcare, Best, The Netherlands.ORCID http://orcid.org/0000-0003-3693-1862
Alejandro TomaselloDepartment of Neurology, Vall d'Hebron University Hospital, Stroke Unit, Barcelona, Spain.
Carlos A MolinaDepartment of Neurology, Vall d'Hebron University Hospital, Stroke Unit, Barcelona, Spain.
Marc RiboDepartment of Neurology, Vall d'Hebron University Hospital, Stroke Unit, Barcelona, Spain marcriboj@hotmail.com.ORCID http://orcid.org/0000-0001-9242-043X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ANGIOCAT trial showed a clinical benefit of direct to angiography suite (DTAS) for patients with large vessel occlusion (LVO) stroke admitted within 6 hours after symptom onset in decreased hospital workflow time and improved clinical outcome. However, the impact of DTAS implementation on hospital costs is unknown. This economic evaluation aims to assess the cost-utility of DTAS from the provider (hospital) perspective.

methodsA cost-utility analysis was applied to compare DTAS with the standard direct to CT (DTCT) suite approach using direct cost and health outcomes data. The time horizon was 90 days. One-way sensitivity analysis as well as probabilistic sensitivity analysis was performed, varying the model parameters by ±25%. Measures included costs, quality-adjusted life years, and incremental cost-effectiveness ratios. Health outcomes, classified according to the modified Rankin Scale, were obtained from the ANGIOCAT trial. Respective utilities were obtained from the literature.

resultsDTAS is the dominant strategy. The incremental cost-effectiveness ratio is -€89 110 (-$97 600) with cost saving per patient of -€2848 (-$3120). The improved clinical outcome is directly related with a decrease in costs for the hospital, mainly due to the decrease in costs of hospital stay, improved clinical outcome and fewer complications.

conclusionsFor patients with LVO admitted within 6 hours after symptom onset, the DTAS not only improves clinical outcome but also decreases the costs (dominant option) compared with the standard DTCT. Multicentric international randomized clinical trials are ongoing to determine the replicability of our findings.

Indexed as

Arterial Occlusive DiseasesIschemic StrokeStrokeAngiographyCost-Benefit AnalysisHumansSpainThrombectomyangiographyeconomicsstrokethrombectomy

Identifiers

PMID37105721
PMCPMC10850729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.