Evidence map›Paper›PMID 37105673›Full record

ArticleBioengineered

Alkannin reverses lipopolysaccharides-induced inflammatory responses by suppressing mitogen-activated protein kinase and nuclear factor kappa-B signalling.

Jingya Yang, Jing Li, Lanzhu Yang, Ruohui Guo

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Exploring the Pharmacological Potential ofMolecules (Basel, Switzerland) · 2024
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jingya YangCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, China.ORCID 0000-0002-6324-8236
Jing LiCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, China.ORCID 0000-0002-1009-6523
Lanzhu YangCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, China.ORCID 0000-0001-9386-1288
Ruohui GuoCollege of Food Science and Technology, Shanghai Ocean University, Shanghai, China.ORCID 0009-0008-6861-9834
Shanghai Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is an inflammatory disease that seriously affects human health worldwide. Meanwhile, inflammation in RAW264.7 cells could lead to the progression of RA. Alkannin (ALK) is derived from

Indexed as

Mitogen-Activated Protein KinasesNF-kappa BAnti-Inflammatory AgentsCyclooxygenase 2HumansInflammationLipopolysaccharidesMAP Kinase Signaling SystemNaphthoquinonesNitric OxideReceptor Protein-Tyrosine KinasesalkanninAnti-Inflammatory AgentsCyclooxygenase 2LipopolysaccharidesMitogen-Activated Protein KinasesNaphthoquinonesNF-kappa BNitric OxideReceptor Protein-Tyrosine KinasesAlkanninarthritisinflammatory responseMAPKNF-κB

Identifiers

PMID37105673
PMCPMC10234216
OpenAlexW4367281412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.