Evidence map›Paper›PMID 37105192›Full record

ArticleLupus2023

Cecilia P Chung, Gul Karakoc, Alyson Dickson, Ge Liu, Jorge L Gamboa, Jonathan D Mosley, Nancy J Cox, Vivian K Kawai

Open access · hybridAbstract read
In one paragraph

Article in Lupus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Cecilia P ChungDivision of Rheumatology and Immunology, Department of Medicine Vanderbilt University Medical Center, Nashville, TN, USA.
Gul KarakocDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Alyson DicksonDivision of Rheumatology and Immunology, Department of Medicine Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-3404-3802
Ge LiuDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Jorge L GamboaDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Jonathan D MosleyDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Nancy J CoxVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Vivian K KawaiDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-5841-2575
Vanderbilt University Medical Center · USUniversity of Miami · USVanderbilt University · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Pharmacogenomics of Arrhythmia TherapyU19HL065962 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RODEN, DAN M · 2010 to 2014
$17.4M
Understanding and preventing HLA-associated drug reactionsP50GM115305 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH, RODEN, DAN M · 2015 to 2019
$13.0M
The Genetic Epemiology of Multiple SclerosisR01NS032830 · NINDS · VANDERBILT UNIVERSITY · PI HAINES, JONATHAN L · 1995 to 2010
$8.9M
Epidemiologic Architecture for Genes Linked to Environment (EAGLE)U01HG004798 · NHGRI · VANDERBILT UNIVERSITY · PI CRAWFORD, DANA C · 2008 to 2013
$8.8M
VESPA: Vanderbilt Electronic Systems for Pharmacogenomic AssessmentRC2GM092618 · NIGMS · VANDERBILT UNIVERSITY · PI DENNY, JOSHUA C., RODEN, DAN M · 2009 to 2010
$6.4M
Vanderbilt Genome Electronic Records ProjectU01HG006378 · NHGRI · VANDERBILT UNIVERSITY · PI RODEN, DAN M · 2011 to 2014
$4.0M
Understanding the genetic risk underlying racial disparities in uterine fibroids - Diversity SupplementR01HD074711 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VELEZ EDWARDS, DIGNA R · 2013 to 2017
$2.9M
Genome and Phenome to Define Disease Risk with Antinuclear AntibodiesR01AR076516 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KAWAI, VIVIAN K · 2020 to 2024
$2.8M
Comparative Safety of Pain MedicationsR01AR073764 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHUNG, CECILIA PILAR · 2019 to 2023
$2.3M
NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243NCRR NIH HHS S10 RR025141NCRR NIH HHS UL1 RR024975NHGRI NIH HHS U01 HG004798NHGRI NIH HHS U01 HG006378NHLBI NIH HHS U19 HL065962NIAMS NIH HHS R01 AR073764NIAMS NIH HHS R01 AR076516NICHD NIH HHS R01 HD074711NIGMS NIH HHS P50 GM115305NIGMS NIH HHS R01 GM130791NIGMS NIH HHS RC2 GM092618NINDS NIH HHS R01 NS032830
6 · The paper itself

Abstract

backgroundSystemic lupus erythematosus (SLE) disproportionately affects individuals of African ancestry (AA) compared to European ancestry (EA). In the general population, high risk (HR) variants in the apolipoprotein L1 (

methodsWe performed a retrospective cohort study in patients with SLE of EA and AA using a genetic biobank linked to de-identified electronic health records.

resultsWe studied 784 patients with SLE; 195 (24.9%) were of AA, of whom 27 (13.8%) had

conclusionThe higher prevalence of renal and hypertensive disorders in SLE patients of AA compared to those of EA is not fully explained by the presence of

Indexed as

Apolipoprotein L1HypertensionKidney Failure, ChronicLupus Erythematosus, SystemicBlack or African AmericanGenetic Predisposition to DiseaseGenotypeHumansRetrospective StudiesRisk FactorsAPOL1 protein, humanApolipoprotein L1APOL1renal outcomesSystemic lupus erythematosus

Identifiers

PMID37105192
PMCPMC10189827
OpenAlexW4367187745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.