Evidence map›Paper›PMID 37104717›Full record

ReviewPhysiological reviews2023

Leveraging physiology and artificial intelligence to deliver advancements in health care.

Angela Zhang, Zhenqin Wu, Eric Wu, Matthew Wu, Michael P Snyder, James Zou, Joseph C Wu

Abstract readReview
In one paragraph

Review in Physiological reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Guidelines for mechanistic modeling and analysis in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Angela ZhangStanford Cardiovascular Institute, School of Medicine, Stanford University, Stanford, California, United States.
Zhenqin WuDepartment of Chemistry, Stanford University, Stanford, California, United States.
Eric WuDepartment of Electrical Engineering, Stanford University, Stanford, California, United States.ORCID 0000-0001-8379-3373
Matthew WuGreenstone Biosciences, Palo Alto, California, United States.
Michael P SnyderDepartment of Genetics, School of Medicine, Stanford University, Stanford, California, United States.ORCID 0000-0003-0784-7987
James ZouDepartment of Biomedical Informatics, School of Medicine, Stanford University, Stanford, California, United States.
Joseph C WuStanford Cardiovascular Institute, School of Medicine, Stanford University, Stanford, California, United States.ORCID 0000-0002-6068-8041

Funding

Role of Single Cell mRNA Variation in Systems Associated Electrically Excitable CU01MH098953 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI EBERWINE, JAMES H, KIM, JUNHYONG · 2012 to 2016
$11.4M
Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCsR01HL130020 · NHLBI · STANFORD UNIVERSITY · PI Ronglih Liao, MARK MERCOLA · 2016 to 2026
$7.3M
Genome Editing of Human iPSCs to Study Inherited Hypertrophic CardiomyopathyR01HL126527 · NHLBI · STANFORD UNIVERSITY · PI QI, LEI STANLEY, WU, JOSEPH C. · 2015 to 2022
$5.4M
Human iPSC Model to Elucidate Metabolic Interplay in Diabetic CardimyopathyR01HL146690 · NHLBI · STANFORD UNIVERSITY · PI LIAO, RONGLIH, MERCOLA, MARK · 2019 to 2025
$5.1M
Stanford Medicine Center for Longevity and Healthy Aging Research Education CoreP30AG059307 · NIA · STANFORD UNIVERSITY · PI PERIYAKOIL, VYJEYANTHI S, YESAVAGE, JEROME A · 2018 to 2025
$4.9M
Elucidating ECM Signaling in Cardiac Organoids with Machine Learning and Single-cell MultiomicsR01HL163680 · NHLBI · STANFORD UNIVERSITY · PI RAJADAS, JAYAKUMAR, WONG, WING H. · 2022 to 2025
$2.5M
Using Deep Learning to Predict Induced Pluripotent Stem Cell-Derived Cardiomyocyte (iPSC-CM) Differentiation OutcomesF30HL156478 · NHLBI · STANFORD UNIVERSITY · PI ZHANG, ANGELA · 2021 to 2023
$118k
NHLBI NIH HHS F30 HL156478NHLBI NIH HHS R01 HL126527NHLBI NIH HHS R01 HL130020NHLBI NIH HHS R01 HL146690NHLBI NIH HHS R01 HL163680NIA NIH HHS P30 AG059307NIMH NIH HHS U01 MH098953
6 · The paper itself

Abstract

Artificial intelligence in health care has experienced remarkable innovation and progress in the last decade. Significant advancements can be attributed to the utilization of artificial intelligence to transform physiology data to advance health care. In this review, we explore how past work has shaped the field and defined future challenges and directions. In particular, we focus on three areas of development. First, we give an overview of artificial intelligence, with special attention to the most relevant artificial intelligence models. We then detail how physiology data have been harnessed by artificial intelligence to advance the main areas of health care: automating existing health care tasks, increasing access to care, and augmenting health care capabilities. Finally, we discuss emerging concerns surrounding the use of individual physiology data and detail an increasingly important consideration for the field, namely the challenges of deploying artificial intelligence models to achieve meaningful clinical impact.

Indexed as

Artificial IntelligenceDelivery of Health CareHumansartificial intelligencehealth caremedicinephysiology

Identifiers

PMID37104717
PMCPMC10390055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.