Evidence map›Paper›PMID 37104570›Full record

ArticleScience (New York, N.Y.)2023

Insights into mammalian TE diversity through the curation of 248 genome assemblies.

Austin B Osmanski, Nicole S Paulat, Jenny Korstian, Jenna R Grimshaw, Michaela Halsey, Kevin A M Sullivan, Diana D Moreno-Santillán, Claudia Crookshanks, Jacquelyn Roberts, Carlos Garcia and 12 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Austin B OsmanskiDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0002-1485-6446
Nicole S PaulatDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0002-6881-2588
Jenny KorstianDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0003-3872-8948
Jenna R GrimshawDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0001-7673-5167
Michaela HalseyDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.
Kevin A M SullivanDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0001-8499-0491
Diana D Moreno-SantillánDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0003-2153-0732
Claudia CrookshanksDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.
Jacquelyn RobertsDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.
Carlos GarciaDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0001-9194-4514
Matthew G JohnsonDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0002-1958-6334
Llewellyn D DensmoreDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0002-6681-5507
Richard D StevensDepartment of Natural Resources Management and Natural Science Research Laboratory, Museum of Texas Tech University, Lubbock, TX, USA.
Zoonomia Consortium†
Jeb RosenInstitute for Systems Biology, Seattle, WA, USA.ORCID 0000-0002-8832-1276
Jessica M StorerInstitute for Systems Biology, Seattle, WA, USA.ORCID 0000-0002-9619-5265
Robert HubleyInstitute for Systems Biology, Seattle, WA, USA.ORCID 0000-0001-9261-3821
Arian F A SmitInstitute for Systems Biology, Seattle, WA, USA.ORCID 0000-0003-2088-3165
Liliana M DávalosDepartment of Ecology & Evolution, Stony Brook University, Stony Brook, NY, USA.ORCID 0000-0002-4327-7697
Elinor K KarlssonDepartment of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-4343-3776
Kerstin Lindblad-TohBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0001-8338-0253
David A RayDepartment of Biological Sciences, Texas Tech University, Lubbock, TX, USA.ORCID 0000-0002-3340-3987

Funding

GENCODE: comprehensive reference genome annotation for human and mouseU24HG007234 · NHGRI · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI Fergal James Martin · 2021 to 2026
$16.1M
Maintenance and Development of RepeatMasker and RepeatModelerR01HG002939 · NHGRI · INSTITUTE FOR SYSTEMS BIOLOGY · PI Robert MacDonald Hubley, Arian Fredericus Anthonius Smit · 2003 to 2026
$9.1M
Dfam: sustainable growth, curation support, and improved quality for mobile element annotationU24HG010136 · NHGRI · INSTITUTE FOR SYSTEMS BIOLOGY · PI Robert MacDonald Hubley, Arian Fredericus Anthonius Smit · 2018 to 2026
$5.2M
The 200 mammals project: sequencing genomes by a novel cost-effective method, yielding a high resolution annotation of the human genome.R01HG008742 · NHGRI · BROAD INSTITUTE, INC. · PI BIRREN, BRUCE W., KARLSSON, ELINOR · 2016 to 2020
$2.8M
Enabling Comparative PangenomicsR01HG010485 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, MARTIN, FERGAL JAMES · 2020 to 2023
$2.6M
NHGRI NIH HHS R01 HG002939NHGRI NIH HHS R01 HG008742NHGRI NIH HHS R01 HG010485NHGRI NIH HHS U24 HG007234NHGRI NIH HHS U24 HG010136
6 · The paper itself

Abstract

We examined transposable element (TE) content of 248 placental mammal genome assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that although mammals resemble one another in total TE content and diversity, they show substantial differences with regard to recent TE accumulation. This includes multiple recent expansion and quiescence events across the mammalian tree. Young TEs, particularly long interspersed elements, drive increases in genome size, whereas DNA transposons are associated with smaller genomes. Mammals tend to accumulate only a few types of TEs at any given time, with one TE type dominating. We also found association between dietary habit and the presence of DNA transposon invasions. These detailed annotations will serve as a benchmark for future comparative TE analyses among placental mammals.

Indexed as

DNA Transposable ElementsEutheriaEvolution, MolecularGenetic VariationAnimalsDatasets as TopicFeeding BehaviorFemaleLong Interspersed Nucleotide ElementsPregnancyDNA Transposable Elements

Identifiers

PMID37104570
PMCPMC11103246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.