Evidence map›Paper›PMID 37104558›Full record

ReviewCirculation research2023

Electronic Nicotine Delivery Systems and Cardiovascular/Cardiometabolic Health.

Matthew J Mears, Harrison L Hookfin, Priya Bandaru, Pablo Vidal, Kristin I Stanford, Loren E Wold

Abstract readReview
In one paragraph

Review in Circulation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Electronic Cigarette Harms: Aggregate Evidence Shows Damage to Biological Systems.International journal of environmental research and public health · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew J MearsDorothy M. Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, College of Medicine and Wexner Medical Center (M.J.M., H.L.H., P.B., P.V., K.I.S., L.E.W.), the Ohio State University, Columbus.ORCID 0000-0003-3833-5634
Harrison L HookfinDorothy M. Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, College of Medicine and Wexner Medical Center (M.J.M., H.L.H., P.B., P.V., K.I.S., L.E.W.), the Ohio State University, Columbus.
Priya BandaruDorothy M. Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, College of Medicine and Wexner Medical Center (M.J.M., H.L.H., P.B., P.V., K.I.S., L.E.W.), the Ohio State University, Columbus.
Pablo VidalDorothy M. Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, College of Medicine and Wexner Medical Center (M.J.M., H.L.H., P.B., P.V., K.I.S., L.E.W.), the Ohio State University, Columbus.ORCID 0000-0002-9036-1533
Kristin I StanfordDorothy M. Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, College of Medicine and Wexner Medical Center (M.J.M., H.L.H., P.B., P.V., K.I.S., L.E.W.), the Ohio State University, Columbus.ORCID 0000-0002-0681-7746
Loren E WoldDorothy M. Davis Heart and Lung Research Institute and Department of Physiology and Cell Biology, College of Medicine and Wexner Medical Center (M.J.M., H.L.H., P.B., P.V., K.I.S., L.E.W.), the Ohio State University, Columbus.ORCID 0000-0001-8155-0204

Funding

Mechanisms of exposure-induced tissue functional and pathological changes in a mouse model of Alzheimer's DiseaseR01AG057046 · NIA · OHIO STATE UNIVERSITY · PI COMBS, COLIN K, DEL MONTE, FEDERICA · 2017 to 2021
$4.0M
Defining the Impact of E-Cigarettes on Cardiac PathophysiologyR01HL139348 · NHLBI · OHIO STATE UNIVERSITY · PI WOLD, LOREN EUGENE · 2017 to 2020
$1.9M
Effects of WTC Dust Exposure on Cardiac and Cognitive FunctionsU01OH012056 · OH · OHIO STATE UNIVERSITY · PI COHEN, MITCHELL D, WOLD, LOREN EUGENE · 2020 to 2020
$500k
NHLBI NIH HHS R01 HL139348NIA NIH HHS R01 AG057046NIOSH CDC HHS U01 OH012056
6 · The paper itself

Abstract

The use of electronic nicotine delivery systems, specifically electronic cigarettes (e-cig), has risen dramatically within the last few years; the demographic purchasing these devices is now predominantly adolescents that are not trying to quit the use of traditional combustible cigarettes, but rather are new users. The composition and appearance of these devices has changed since their first entry into the market in the late 2000s, but they remain composed of a battery and aerosol delivery system that is used to deliver breakdown products of propylene glycol/vegetable glycerin, flavorings, and potentially nicotine or other additives. Manufacturers have also adjusted the type of nicotine that is used within the liquid to make the inhalation more palatable for younger users, further affecting the number of youth who use these devices. Although the full spectrum of cardiovascular and cardiometabolic consequences of e-cig use is not fully appreciated, data is beginning to show that e-cigs can cause both short- and long-term issues on cardiac function, vascular integrity and cardiometabolic issues. This review will provide an overview of the cardiovascular, cardiometabolic, and vascular implications of the use of e-cigs, and the potential short- and long-term health effects. A robust understanding of these effects is important in order to inform policy makers on the dangers of e-cigs use.

Indexed as

Cardiovascular DiseasesElectronic Nicotine Delivery SystemsVapingAdolescentHumansLungNicotineNicotineaerosolsnicotinepropylene glycoltobacco productsvaping

Identifiers

PMID37104558
PMCPMC10154046

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.