Evidence map›Paper›PMID 37104337›Full record

ArticleTropical medicine and infectious disease2023

Wastewater Surveillance Can Function as an Early Warning System for COVID-19 in Low-Incidence Settings.

Mohamad Assoum, Colleen L Lau, Phong K Thai, Warish Ahmed, Jochen F Mueller, Kevin V Thomas, Phil Min Choi, Greg Jackson, Linda A Selvey

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mohamad AssoumSchool of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4006, Australia.ORCID 0000-0001-5857-4814
Colleen L LauSchool of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4006, Australia.ORCID 0000-0001-8288-4169
Phong K ThaiQueensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD 4102, Australia.
Warish AhmedCSIRO Land and Water, Ecosciences Precinct, 41 Boggo Road, Dutton Park, QLD 4102, Australia.
Jochen F MuellerQueensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD 4102, Australia.
Kevin V ThomasQueensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD 4102, Australia.ORCID 0000-0002-2155-100X
Phil Min ChoiHealth Protection Branch, Queensland Health, Brisbane, QLD 4006, Australia.
Greg JacksonHealth Protection Branch, Queensland Health, Brisbane, QLD 4006, Australia.ORCID 0000-0001-6748-8301
Linda A SelveySchool of Public Health, Faculty of Medicine, The University of Queensland, Brisbane, QLD 4006, Australia.ORCID 0000-0001-8493-0974

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDuring the first two years of the COVID-19 pandemic, Australia implemented a series of international and interstate border restrictions. The state of Queensland experienced limited COVID-19 transmission and relied on lockdowns to stem any emerging COVID-19 outbreaks. However, early detection of new outbreaks was difficult. In this paper, we describe the wastewater surveillance program for SARS-CoV-2 in Queensland, Australia, and report two case studies in which we aimed to assess the potential for this program to provide early warning of new community transmission of COVID-19. Both case studies involved clusters of localised transmission, one originating in a Brisbane suburb (Brisbane Inner West) in July-August 2021, and the other originating in Cairns, North Queensland in February-March 2021. MATERIALS AND

methodsPublicly available COVID-19 case data derived from the notifiable conditions (NoCs) registry from the Queensland Health data portal were cleaned and merged spatially with the wastewater surveillance data using statistical area 2 (SA2) codes. The positive predictive value and negative predictive value of wastewater detection for predicting the presence of COVID-19 reported cases were calculated for the two case study sites.

resultsEarly warnings for local transmission of SARS-CoV-2 through wastewater surveillance were noted in both the Brisbane Inner West cluster and the Cairns cluster. The positive predictive value of wastewater detection for the presence of notified cases of COVID-19 in Brisbane Inner West and Cairns were 71.4% and 50%, respectively. The negative predictive value for Brisbane Inner West and Cairns were 94.7% and 100%, respectively.

conclusionsOur findings highlight the utility of wastewater surveillance as an early warning tool in low COVID-19 transmission settings.

Indexed as

early warningSARS-CoV-2surveillancewastewater surveillance

Identifiers

PMID37104337
PMCPMC10143724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.