SynthesisPloS one2023
Sex-based differences in long-term outcomes after stroke: A meta-analysis.
Synthesis in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed.
- Changes in Life Expectancy After Stroke Among Americans Aged 50 and Above by Sex, 1996-2018.Journal of the American Geriatrics Society · 2026Article
- Article
- Sex-Related Differences in Outcomes of Endovascular Treatment of Distal Medium Vessel Occlusion Strokes.Clinical neuroradiology · 2026Article
- Review
- The Impact of Comorbidities on Functional Outcomes After Rehabilitation in Stroke Patients.Healthcare (Basel, Switzerland) · 2026Article
- Sex-Difference in Stroke Outcome in Young People in Relation to Haemoglobin Level.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Functional Recovery After Stroke and Its Association with Patient's Quality of Life and Caregiver Burden.Journal of clinical medicine · 2026Article
- A multimodal individualized long-term intervention to prevent functional decline after stroke (LAST-long): a single blinded randomised controlled trial.The Lancet regional health. Europe · 2026Article
- Sex and gender-related differences in neurological diseases: current challenges and recommendations for clinical practice.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Review
- Multivariate data analysis of sex differences in emotional and cognitive evaluations over 1 year after stroke.Scientific reports · 2025Observational
- Predictor Role ofMedicina (Kaunas, Lithuania) · 2025Article
- Sex Differences in Stroke Risk Factors and Mechanisms in a Multi-Ethnic Asian Population.Journal of cardiovascular development and disease · 2025Article
- Identifying individuals at risk of post-stroke depression: Development and validation of a predictive model.Saudi medical journal · 2025Article
- Fatty Acid Ratios Versus Conventional Risk Factors in Stroke: Insights into Severe Disability and Mortality Outcomes.Nutrients · 2025Article
- Predictors of functional deterioration from 90 days to 1 year after endovascular treatment for vertebrobasilar artery occlusion: a multicenter retrospective study.Frontiers in neurology · 2025Article
- Sex Differences in Profile and In-Hospital Death for Acute Stroke in Chile: Data From a Nationwide Hospital Registry.Journal of the American Heart Association · 2024Article
- Major vascular events after first incident stroke: a population-based study.BMJ neurology open · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited data on sex-related disparities in the long-term outcomes after stroke. We aim to investigate whether there are sex-based differences in long-term outcomes using pooled data.
methodsThree databases (PubMed, Embase, and Cochrane Library) were systematically searched from inception to July 2022. This meta-analysis was performed in accordance with the recommendations and guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The modified Newcastle-Ottawa scale was used to assess the risk of bias. In addition, a random-effects model was used.
resultsTwenty-two cohort studies with 84538 patients were included. There were 50.2% men and 49.8% women. Women had a higher mortality at 1 (odds ration [OR], 0.82; 95% confidence interval [CI][0.69, 0.99], P = 0.03) and 10 (OR 0.72, 95% CI[0.65, 0.79], P < 0.00001) years, higher stroke recurrence at 1 year (OR 0.85, 95% CI[0.73, 0.98], P = 0.02), lower favorable outcome at 1 year (OR 1.36, 95% CI[1.24, 1.49], P < 0.00001). No significant difference was detected between men and women in the outcomes of health-related quality of life and depression.
conclusionIn this meta-analysis, the 1- and 10-year mortality and stroke recurrence rates were higher in female patients than in male patients after stroke. In addition, females tended to experience less favorable outcomes in the first year after stroke. Finally, further long-term studies on sex disparities in stroke prevention, care, and management are warranted to explore the opportunities to reduce this gap.
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