Evidence map›Paper›PMID 37104207›Full record

ArticleToxins2023

Chimeric Peptides from

Salvador Dueñas, Teresa Escalante, Jahaziel Gasperin-Bulbarela, Johanna Bernáldez-Sarabia, Karla Cervantes-Luévano, Samanta Jiménez, Noemí Sánchez-Campos, Olivia Cabanillas-Bernal, Blanca J Valdovinos-Navarro, Angélica Álvarez-Lee and 2 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Salvador DueñasDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.
Teresa EscalanteInstituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José 11501, Costa Rica.
Jahaziel Gasperin-BulbarelaDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0001-6591-3968
Johanna Bernáldez-SarabiaDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0003-4894-5604
Karla Cervantes-LuévanoDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.
Samanta JiménezDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0002-0363-0310
Noemí Sánchez-CamposDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0001-9572-8587
Olivia Cabanillas-BernalDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.
Blanca J Valdovinos-NavarroDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0003-2017-9127
Angélica Álvarez-LeeDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.
Marco A De León-NavaDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0003-1873-6676
Alexei F Licea-NavarroDepartamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada C.P. 22860, Mexico.ORCID 0000-0003-4022-7405
Centro de Investigación Científica y de Educación Superior de Ensenada · MXUniversidad de Costa Rica · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research into various proteins capable of blocking metabolic pathways has improved the detection and treatment of multiple pathologies associated with the malfunction and overexpression of different metabolites. However, antigen-binding proteins have limitations. To overcome the disadvantages of the available antigen-binding proteins, the present investigation aims to provide chimeric antigen-binding peptides by binding a complementarity-determining region 3 (CDR3) of variable domains of new antigen receptors (VNARs) with a conotoxin. Six non-natural antibodies (NoNaBodies) were obtained from the complexes of conotoxin cal14.1a with six CDR3s from the VNARs of

Indexed as

ConotoxinsGastropodaSharksAnimalsAntibodiesAntigensCarrier ProteinsPeptidesVascular Endothelial Growth Factor AAntibodiesAntigensCarrier ProteinsConotoxinsPeptidesVascular Endothelial Growth Factor Achimeric peptideminiprotein designNoNaBodyprotein scaffoldVNAR and conotoxin fusion

Identifiers

PMID37104207
PMCPMC10141372
OpenAlexW4362639834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.