Evidence map›Paper›PMID 37104153›Full record

ArticleSports (Basel, Switzerland)2023

Nine Months of Hybrid Intradialytic Exercise Training Improves Ejection Fraction and Cardiac Autonomic Nervous System Activity.

Christoforos D Giannaki, Stefania S Grigoriou, Keith George, Christina Karatzaferi, Paris Zigoulis, Eleftherios Lavdas, Dimitrios Chaniotis, Ioannis Stefanidis, Giorgos K Sakkas

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sports (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07780175 (The Effects of Long-Term Hybrid Intradialytic Exercise on Cognitive Function and Quality of Life in End-Stage Kidney Disease Patients), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07780175 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

The Effects of Long-Term Hybrid Intradialytic Exercise on Cognitive Function and Quality of Life in End-Stage Kidney Disease Patients: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of ThessalyRan2026 to 2027Enrolled60ConditionsSupportive Care, Exercise Adaptations, Exercise Training Therapy, Clinical ExerciseArmsResistance Training, Aerobic training, Combination Training
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Just Do It- Exercise before or during Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Christoforos D GiannakiDepartment of Life Sciences, University of Nicosia, Nicosia 2417, Cyprus.ORCID 0000-0003-0029-1189
Stefania S GrigoriouSchool of Physical Education, Sport Science and Dietetics, University of Thessaly, 42100 Trikala, Greece.
Keith GeorgeResearch Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool L2 2QP, UK.
Christina KaratzaferiSchool of Physical Education, Sport Science and Dietetics, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0002-8266-5780
Paris ZigoulisDepartment of Medicine, School of Health Science, University of Thessaly, 38221 Larissa, Greece.
Eleftherios LavdasDepartment of Biomedical Sciences, University of West Attica, 12243 Athens, Greece.
Dimitrios ChaniotisDepartment of Biomedical Sciences, University of West Attica, 12243 Athens, Greece.ORCID 0000-0003-2313-1305
Ioannis StefanidisDepartment of Medicine, School of Health Science, University of Thessaly, 38221 Larissa, Greece.
Giorgos K SakkasSchool of Physical Education, Sport Science and Dietetics, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0002-2462-995X
University of Thessaly · GRUniversity of West Attica · GRLiverpool John Moores University · GBUniversity of Nicosia · CY

Funding

European Union Horizon 2020 Research and Innovation Programme-H2020 MSCAS-RISE 645648
6 · The paper itself

Abstract

Cardiovascular disease is the most common cause of death in hemodialysis (HD) patients. Intradialytic aerobic exercise training has a beneficial effect on cardiovascular system function and reduces mortality in HD patients. However, the impact of other forms of exercise on the cardiovascular system, such as hybrid exercise, is not clear. Briefly, hybrid exercise combines aerobic and strength training in the same session. The present study examined whether hybrid intradialytic exercise has long-term benefits on left ventricular function and structure and the autonomous nervous system in HD patients. In this single-group design, efficacy-based intervention, twelve stable HD patients (10M/2F, 56 ± 19 years) participated in a nine-month-long hybrid intradialytic training program. Both echocardiographic assessments of left ventricular function and structure and heart rate variability (HRV) were assessed pre, during and after the end of the HD session at baseline and after the nine-month intervention. Ejection Fraction (EF), both assessed before and at the end of the HD session, appeared to be significantly improved after the intervention period compared to the baseline values (48.7 ± 11.1 vs. 58.8 ± 6.5,

Indexed as

2 d doppler echocardiographycardiac functionexercisehemodialysis

Identifiers

PMID37104153
PMCPMC10143437
OpenAlexW4362583487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.