Evidence map›Paper›PMID 37104129›Full record

ArticleTomography (Ann Arbor, Mich.)2023

Textural Features of Mouse Glioma Models Measured by Dynamic Contrast-Enhanced MR Images with 3D Isotropic Resolution.

Karl Kiser, Jin Zhang, Sungheon Gene Kim

Abstract read
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Karl KiserDepartment of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.
Jin ZhangDepartment of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.
Sungheon Gene KimDepartment of Radiology, Weill Cornell Medical College, New York, NY 10065, USA.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
DCE MRI Study for Breast Cancer.R01CA160620 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE · 2012 to 2023
$5.4M
Gradient-Echo Spectroscopic Imaging Study of Saturated Fat and Breast CancerR01CA219964 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE, MOY, LINDA · 2018 to 2022
$2.3M
7T Small Animal MRI Scanner Replacement for Translational Imaging ResourceS10OD018337 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BOADA, FERNANDO E · 2014 to 2014
$2.0M
Diffusion MRI of Treatment Response for De-escalation of Radiation TherapyUG3CA228699 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIM, SUNGHEON GENE · 2019 to 2020
$807k
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA160620NCI NIH HHS R01 CA219964NCI NIH HHS UG3 CA228699NIH HHS S10 OD018337
6 · The paper itself

Abstract

This paper investigates the effect of anisotropic resolution on the image textural features of pharmacokinetic (PK) parameters of a murine glioma model using dynamic contrast-enhanced (DCE) MR images acquired with an isotropic resolution at 7T with pre-contrast T1 mapping. The PK parameter maps of whole tumors at isotropic resolution were generated using the two-compartment exchange model combined with the three-site-two-exchange model. The textural features of these isotropic images were compared with those of simulated, thick-slice, anisotropic images to assess the influence of anisotropic voxel resolution on the textural features of tumors. The isotropic images and parameter maps captured distributions of high pixel intensity that were absent in the corresponding anisotropic images with thick slices. A significant difference was observed in 33% of the histogram and textural features extracted from anisotropic images and parameter maps, compared to those extracted from corresponding isotropic images. Anisotropic images in different orthogonal orientations demonstrated 42.1% of the histogram and textural features to be significantly different from those of isotropic images. This study demonstrates that the anisotropy of voxel resolution needs to be carefully considered when comparing the textual features of tumor PK parameters and contrast-enhanced images.

Indexed as

GliomaMagnetic Resonance ImagingAnimalsImage EnhancementMicedynamic contrast-enhanced MRIimage textureisotropic resolutionradiomics

Identifiers

PMID37104129
PMCPMC10141208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.