Evidence map›Paper›PMID 37104020›Full record

ArticleMethods and protocols2023

Critical Evaluation of Embedding Media for Histological Studies of Early Stages of Chick Embryo Development.

Melyssa Kmecick, Mariliza Cristine Vieira da Costa, Eduardo da Costa Ferreira, Maritana Mela Prodocimo, Claudia Feijó Ortolani-Machado

Abstract read
In one paragraph

Article in Methods and protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Histological Processing of Scaffolds: Challenges and Solutions.Journal of functional biomaterials · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melyssa KmecickLaboratory of Embryotoxicology, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Av. Cel. Francisco Heráclito dos Santos, 100, Curitiba 81.531-980, PR, Brazil.ORCID 0000-0002-8383-5091
Mariliza Cristine Vieira da CostaLaboratory of Embryotoxicology, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Av. Cel. Francisco Heráclito dos Santos, 100, Curitiba 81.531-980, PR, Brazil.
Eduardo da Costa FerreiraLaboratory of Embryotoxicology, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Av. Cel. Francisco Heráclito dos Santos, 100, Curitiba 81.531-980, PR, Brazil.
Maritana Mela ProdocimoLaboratory of Cell Toxicology, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Av. Cel. Francisco Heráclito dos Santos, 100, Curitiba 81.531-980, PR, Brazil.
Claudia Feijó Ortolani-MachadoLaboratory of Embryotoxicology, Department of Cell Biology, Biological Sciences Sector, Federal University of Paraná, Av. Cel. Francisco Heráclito dos Santos, 100, Curitiba 81.531-980, PR, Brazil.ORCID 0000-0002-0523-6624

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88882.382540/2019-01
6 · The paper itself

Abstract

A histological examination is an important tool in embryology, developmental biology, and correlated areas. Despite the amount of information available about tissue embedding and different media, there is a lack of information regarding best practices for embryonic tissues. Embryonic tissues are considered fragile structures, usually small in size, and frequently challenging to position correctly in media for the subsequent histological steps. Here, we discuss the embedding media and procedures that provided us with appropriate preservation of tissue and easier orientation of embryos at early development. Fertilized

Indexed as

chick embryohistological processinghistoresinparaplastpolyethylene glycol

Identifiers

PMID37104020
PMCPMC10146326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.