Evidence map›Paper›PMID 37104001›Full record

Trial reportJournal of medical Internet research2023

Efficacy of a Mobile Phone-Based Intervention on Health Behaviors and HIV/AIDS Treatment Management: Randomized Controlled Trial.

Bach Xuan Tran, Thu Minh Bui, Anh Linh Do, Laurent Boyer, Pascal Auquier, Long Hoang Nguyen, Anh Hai Tran Nguyen, Toan Van Ngo, Carl A Latkin, Melvyn W B Zhang and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Bach Xuan Tran *Institute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.ORCID 0000-0002-2191-3947
Thu Minh Bui *Bach Mai Medical College, Bach Mai Hospital, Hanoi, Vietnam.ORCID 0000-0002-4457-1038
Anh Linh DoInstitute of Health Economics and Technology, Hanoi, Vietnam.ORCID 0000-0003-3518-2003
Laurent BoyerResearch Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France.ORCID 0000-0003-1229-6622
Pascal AuquierResearch Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France.ORCID 0000-0003-3496-1996
Long Hoang NguyenDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-2601-7647
Anh Hai Tran NguyenInstitute of Health Economics and Technology, Hanoi, Vietnam.ORCID 0009-0008-7241-0523
Toan Van NgoInstitute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.ORCID 0009-0003-4746-6772
Carl A LatkinBloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States.ORCID 0000-0002-7931-2116
Melvyn W B ZhangLee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore.ORCID 0000-0001-8385-2345
Cyrus S H HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-7092-9566
Roger C M HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0001-9629-4493
Aix-Marseille Université · FRJohns Hopkins University · USNational University of Singapore · SGBạch Mai Hospital · VNHanoi Medical University · VNKarolinska Institutet · SENanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) is considered the most important intervention for HIV-positive patients; thus, encouraging the use of and adherence to ART are vital to HIV treatment outcomes. Advances in web and mobile technologies hold potential in supporting HIV treatment management.

objectiveThe aim of this study was to evaluate the feasibility and efficacy of a theory-based mobile health (mHealth) intervention on health behaviors and HIV treatment adherence among patients with HIV/AIDS in Vietnam.

methodsWe performed a randomized controlled trial on 425 HIV patients in two of the largest HIV clinics in Hanoi, Vietnam. Both the intervention group (238 patients) and the control group (187 patients) received regular consultations with doctors and then participated in 1-month and 3-month follow-up visits. Patients in the intervention group received a theory-driven smartphone app to facilitate medication adherence and self-efficacy in HIV patients. Measurements were developed based on the Health Belief Model, which included the visual analog scale of ART Adherence, HIV Treatment Adherence Self-Efficacy Scale, and HIV Symptom Management Self-Efficacy Scale. We also included the 9-item Patient Health Questionnaire (PHQ-9) to assess patients' mental health throughout treatment.

resultsIn the intervention group, the adherence score increased significantly (β=1.07, 95% CI .24-1.90) after 1 month, whereas the HIV adherence self-efficacy was significantly higher after 3 months (β=2.17, 95% CI 2.07-2.27) compared to the control group. There was a positive but low level of change in risk behaviors such as drinking, smoking, and drug use. Factors related to positive change in adherence were being employed and having stable mental well-being (lower PHQ-9 scores). Factors associated with self-efficacy in treatment adherence and symptom management were gender, occupation, younger age, and having no other underlying conditions. A longer duration of ART increased treatment adherence but decreased self-efficacy in symptom management.

conclusionsOur study demonstrated that the mHealth app could improve the overall ART adherence self-efficacy of patients. Further studies with larger sample sizes and longer follow-up periods are needed to support our findings.

trial registrationThai Clinical Trials Registry TCTR20220928003; https://www.thaiclinicaltrials.org/show/TCTR20220928003.

Indexed as

Cell PhoneHealth BehaviorHIV InfectionsMobile ApplicationsAcquired Immunodeficiency SyndromeHumansMedication AdherenceAIDSapplicationbehaviorcareefficacyfeasibilityHIVHIV/AIDSinterventionmanagementmHealthmobile healthself-efficacytreatmenttreatment adherenceVietnam

Identifiers

PMID37104001
PMCPMC10176129
OpenAlexW4367174580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.