Evidence map›Paper›PMID 37103992›Full record

ArticleMicrobial genomics2023

The possible impact of novel mutations in human papillomavirus 52 on the infection characteristics.

Yingxin Gong, Yan Wang, Qi Zhou, Wenjie Qu, Fang Chen, Yaping Wang, Jiayin Mo, Hongwei Zhang, Lin Lin, Tianyi Bi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Microbial genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yingxin GongDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Yan WangDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Qi ZhouDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Wenjie QuDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Fang ChenDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Yaping WangDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Jiayin MoDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Hongwei ZhangDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Lin LinDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Tianyi BiDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Xujie WangDepartment of Obstetrics and Gynecology, Shanghai Changning Maternity and Infant Health Hospital, Shanghai, PR China.
Jiashi GuDepartment of Obstetrics and Gynecology, Shanghai Pudong Hospital of Fudan University, Shanghai, PR China.
Long SuiDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Yanyun LiDepartment of Gynecology and Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
Obstetrics and Gynecology Hospital of Fudan University · CNFudan University · CNShanghai Changning Maternity and Infant Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus 52 (HPV52) infection is prevalent in the Chinese population, and variations in HPV52 show correlations with oncogenicity. However, no specific variation in HPV52 was reported to show relevancy to infection characteristics. In this study, we retrieved 222 isolates of E6 and L1 full-length genes from 197 Chinese women with HPV52 infection. After sequence alignment and phylogenetic tree construction, we found that 98.39 % of the collected variants belonged to the sublineage B2 and two variants displayed incongruence between the phylogenetic tree of E6 and L1. The analysis of the infection pattern showed that the presence of C6480A/T mutation in the L1 gene was associated with single infection (

Indexed as

Genetic VariationHuman Papillomavirus VirusesFemaleHumansMutationPapillomaviridaePhylogenyPolymorphism, Geneticcervical cancerHuman papillomavirusmultiple infectionpersistent infectionvaccine breakthrough infectionvariation

Identifiers

PMID37103992
PMCPMC10210937
OpenAlexW4367174882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.