Evidence map›Paper›PMID 37103885›Full record

ArticleMagnetic resonance in medicine2023

Time-dependent diffusion MRI using multiple stimulated echoes.

Guangyu Dan, Kaibao Sun, Qingfei Luo, Xiaohong Joe Zhou

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Diffusion MRI of the Body: Beyond PGSE-EPI.Journal of magnetic resonance imaging : JMRI · 2026
    Review
  2. Article
  3. Dynamical anomalous transport of molecules subject to inhomogeneous body forces.Zeitschrift fuer angewandte mathematik und physik · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guangyu DanCenter for Magnetic Resonance Research, University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA.ORCID 0000-0003-0427-5661
Kaibao SunCenter for Magnetic Resonance Research, University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA.ORCID 0000-0001-6923-5914
Qingfei LuoCenter for Magnetic Resonance Research, University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA.ORCID 0000-0001-5574-817X
Xiaohong Joe ZhouCenter for Magnetic Resonance Research, University of Illinois College of Medicine at Chicago, Chicago, Illinois, USA.

Funding

A High-End 3 Tesla Human MRI Scanner Dedicated to ResearchS10RR028898 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHOU, XIAOHONG JOE · 2010 to 2010
$2.9M
Probing Intra-voxel Tissue Heterogeneity Using MRIR01EB026716 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHOU, XIAOHONG JOE · 2018 to 2022
$1.7M
NCRR NIH HHS S10 RR028898NIBIB NIH HHS R01 EB026716
6 · The paper itself

Abstract

purposeTo develop a time-efficient pulse sequence that acquires multiple diffusion-weighted images with distinct diffusion times in a single shot by using multiple stimulated echoes (mSTE) with variable flip angles (VFA).

methodsThe proposed diffusion-weighted mSTE with VFA (DW-mSTE-VFA) sequence begins with two 90° RF pulses that straddle a diffusion gradient lobe (G

resultsIn the phantom experiment, the mean ADC measured at different diffusion times using DW-mSTE-VFA were highly consistent (r = 0.999) with those from a commercial spin-echo diffusion-weighted EPI sequence. In the fruit and brain experiments, DW-mSTE-VFA exhibited similar diffusion-time dependence to a standard diffusion-weighted stimulated echo sequence. The ADC showed significant time dependence in the human brain (p = 0.003 in both white matter and gray matter) and prostate tissues (p = 0.003 in both peripheral zone and central gland).

conclusionDW-mSTE-VFA offers a time-efficient tool for investigating the diffusion-time dependency in diffusion MRI studies.

Indexed as

Diffusion Magnetic Resonance ImagingProstateBrainEcho-Planar ImagingGray MatterHeadHumansMaleDWIstimulated echotime-dependent diffusion MRIvariable flip angle

Identifiers

PMID37103885
PMCPMC10330017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.