Evidence map›Paper›PMID 37103835›Full record

ArticleMembranes2023

The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2.

Laura H John, Fiona B Naughton, Mark S P Sansom, Andreas Haahr Larsen

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Laura H JohnDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID 0000-0003-2349-0201
Fiona B NaughtonDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID 0000-0003-0162-1346
Mark S P SansomDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Andreas Haahr LarsenDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.ORCID 0000-0002-2230-2654
University of Oxford · GBUniversity of Copenhagen · DK

Funding

Carlsberg Foundation CF19-0288Lundbeck Foundation R347-2020-2339
6 · The paper itself

Abstract

Phosphatase and tensin homologue (PTEN) and SH2-containing inositol 5'-phosphatase 2 (SHIP2) are structurally and functionally similar. They both consist of a phosphatase (Ptase) domain and an adjacent C2 domain, and both proteins dephosphorylate phosphoinositol-tri(3,4,5)phosphate, PI(3,4,5)P

Indexed as

C2 domainMDphosphatasephosphoinositolPIPPTENSHIP2

Identifiers

PMID37103835
PMCPMC10146288
OpenAlexW4362611885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.