Evidence map›Paper›PMID 37103686›Full record

SynthesisMolecular neurobiology2023

Research on the Potential Biomarkers of Mild Traumatic Brain Injury: a Systematic Review and Bibliometric Analysis.

Yishu Liu, Chudong Wang, Zhiyun Pi, Tingting Wang, Changquan Zhang, Jifeng Cai

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yishu LiuDepartment of Forensic Science, School of Basic Medical Science, Central South University, Changsha, 410013, Hunan, China.
Chudong WangDepartment of Forensic Science, School of Basic Medical Science, Central South University, Changsha, 410013, Hunan, China.
Zhiyun PiDepartment of Forensic Science, School of Basic Medical Science, Central South University, Changsha, 410013, Hunan, China.
Tingting WangDepartment of Forensic Science, School of Basic Medical Science, Central South University, Changsha, 410013, Hunan, China.
Changquan ZhangDepartment of Forensic Science, School of Basic Medical Science, Central South University, Changsha, 410013, Hunan, China. zcq1105@163.com.
Jifeng CaiDepartment of Forensic Science, School of Basic Medical Science, Central South University, Changsha, 410013, Hunan, China. cjf_jifeng@163.com.ORCID http://orcid.org/0000-0003-1443-2712

Funding

National Natural Science Foundation of China No. 81971791
6 · The paper itself

Abstract

Reliable diagnostic methods for mild traumatic brain injury (mTBI) are lacking, and many researchers continue to search for objective biomarkers that can both define and detect mTBI. Although much research has been conducted in this field, there have not been many bibliometric studies. In this study, we aim to analyze the development over the last two decades in scientific output relating to the diagnosis of mTBI. To do this, we extracted documents from Web of Science, PubMed, and Embase and performed descriptive analysis (number of publications, primary journals, authors, and countries/regions), trend topics analysis, and citation analysis for papers across the globe, with a particular focus on molecular markers. One thousand twenty-three publications spanning 390 journals were identified on Web of Science, PubMed, and Embase for the period from 2000 to 2022. The number of publications increased every year (from 2 in 2000 to 137 in 2022). Of all the publications we analyzed, 58.7% had authors from the USA. Our analysis shows that molecular markers are the most studied markers in the field of mTBI diagnostics, accounting for 28.4% of all publications, and that the number of studies focused on this specific aspect has increased sharply in the past 5 years, indicating that molecular markers may become a research trend in the future.

Indexed as

Brain ConcussionBibliometricsBiomarkersForecastingHumansBiomarkersBiomarkersDiagnosisHead injuryMild traumatic brain injury

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.