Evidence map›Paper›PMID 37103497›Full record

ArticleUrology practice2023

Effects of In-office Dispensing by Single-specialty Urology Practices on Management of Advanced Prostate Cancer.

Lillian Y Lai, Samuel R Kaufman, Mary Oerline, Megan E V Caram, Avinash Maganty, Vahakn B Shahinian, Brent K Hollenbeck

Abstract read
In one paragraph

Article in Urology practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lillian Y LaiDepartment of Urology, University of Michigan Medical School, Ann Arbor, Michigan.
Samuel R KaufmanDepartment of Urology, University of Michigan Medical School, Ann Arbor, Michigan.
Mary OerlineDepartment of Urology, University of Michigan Medical School, Ann Arbor, Michigan.
Megan E V CaramVeterans Affairs Health Services Research & Development, Center for Clinical Management and Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.
Avinash MagantyDepartment of Urology, University of Michigan Medical School, Ann Arbor, Michigan.ORCID 0000-0001-6436-6667
Vahakn B ShahinianDepartment of Urology, University of Michigan Medical School, Ann Arbor, Michigan.
Brent K HollenbeckDepartment of Urology, University of Michigan Medical School, Ann Arbor, Michigan.

Funding

Advanced Training in Urologic OncologyT32CA180984 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ganesh S Palapattu, VAHAKN B SHAHINIAN · 2014 to 2026
$3.4M
Aligning financial incentives to promote rational use of active surveillance for prostate cancerR01CA269367 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRENT K. HOLLENBECK, VAHAKN B SHAHINIAN · 2022 to 2026
$2.8M
Impact of urologist practice organization and health policy on prostate cancer treatment, overtreatment and spendingR01HS025707 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOLLENBECK, BRENT K., SHAHINIAN, VAHAKN B · 2017 to 2021
$1.7M
Impact of the Merit-Based Incentive Payment System on the Quality of Prostate Cancer CareF32CA275021 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MAGANTY, AVINASH · 2022 to 2022
$86k
AHRQ HHS R01 HS025707NCI NIH HHS F32 CA275021NCI NIH HHS R01 CA269367NCI NIH HHS T32 CA180984
6 · The paper itself

Abstract

introductionWe examine changes in the volume of patients with advanced prostate cancer and prescriptions for abiraterone and enzalutamide among urology practices with and without in-office dispensing.

methodsUsing data from the National Council for Prescription Drug Programs, we identified in-office dispensing by single-specialty urology practices from 2011 to 2018. As the greatest growth in implementing dispensing occurred among large groups in 2015, outcomes were measured at the practice level in 2014 (before) and 2016 (after) for dispensing and non-dispensing practices. Outcomes included the volume of men with advanced prostate cancer managed by a practice and prescriptions for abiraterone and/or enzalutamide. Using national Medicare data, generalized linear mixed models were fit to compare the practice-level ratio of each outcome (2016 relative to 2014) adjusting for regional contextual factors.

resultsIn-office dispensing increased from 1% to 30% of single-specialty urology practices from 2011 to 2018, with 28 practices implementing dispensing in 2015. In 2016 compared to 2014, adjusted changes in the volume of patients with advanced prostate cancer managed by a practice were similar between non-dispensing (0.88, 95% CI 0.81-0.94) and dispensing (0.93, 95% CI 0.76-1.09) practices (

conclusionsIn-office dispensing is increasingly common in urology practices. This emerging model is not associated with changes in patient volume but is associated with increased prescriptions for abiraterone and enzalutamide.

Indexed as

Prostatic Neoplasms, Castration-ResistantUrologyAbiraterone AcetateAgedBenzamidesHumansMaleMedicareNitrilesPhenylthiohydantoinUnited StatesAbiraterone AcetateBenzamidesenzalutamideNitrilesPhenylthiohydantoinabiraterone acetateenzalutamidepharmacyprostatic neoplasms

Identifiers

PMID37103497
PMCPMC10154036

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.