Evidence map›Paper›PMID 37103088›Full record

ArticleIn vivo (Athens, Greece)

Emotional Distress Prior to Chemoradiation for Rectal or Anal Cancer.

Dirk Rades, Ahmed Al-Salool, Nathan Y Yu, Tobias Bartscht

Registry-linked trialAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06496438 (Psychobiotics Ameliorate Anxiety and Depression Status in Patients Under Chemotherapy for Gastrointestinal Malignancies), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06496438 naunknown statusnot on this map

Psychobiotics Ameliorate Anxiety and Depression Status in Patients Under Chemotherapy for Gastrointestinal Malignancies

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2023 to 2025Enrolled270ConditionsDepression, Anxiety Disorder, Probiotics, Gastrointestinal CancerArmsPsychobiotics, Placebo
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Patients' perspective in anal cancer.ESMO gastrointestinal oncology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany; dirk.rades@uksh.de.
Ahmed Al-SaloolDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Nathan Y YuDepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, U.S.A.
Tobias BartschtDepartment of Hematology, Oncology and Stem Cell Transplantation, MSH Medical School Hamburg, Schwerin Campus, Schwerin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAnticipation of chemoradiation has been reported to cause psychosocial distress in patients with rectal cancer. This study provides additional data regarding prevalence and risk factors of emotional distress in patients who received chemoradiation for rectal or anal cancer. PATIENTS AND

methodsSixty-four patients were analyzed for emotional distress utilizing 12 factors. When applying the Bonferroni correction, p-values <0.0042 were considered significant.

resultsWorry, fears, sadness, depression, nervousness, and loss of interest in usual activities were reported by 31%, 47%, 33%, 11%, 47%, and 19% of patients, respectively. More physical problems were associated with fears (p=0.0030) and loss of interest (p=0.0021). Strong trends were observed for associations between female sex and sadness (p=0.0098) and between lower performance score and worry (p=0.0068) or fears (p=0.0064).

conclusionA considerable proportion of patients reported emotional distress prior to chemoradiation for rectal or anal cancer. High-risk patients may benefit from early psycho-oncological support.

Indexed as

Anus NeoplasmsPsychological DistressRectal NeoplasmsChemoradiotherapyFemaleHumansRectumanal cancerchemoradiationemotional distressRectal cancer

Identifiers

PMID37103088
PMCPMC10188002

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.